This Week in #MathOnco
This week in
Mathematical Oncology
January 18, 2018 ~ Issue 5
From the editor
Welcome to the latest edition of "This week in Mathematical Oncology." Today's issue has some exciting publications ranging from evolutionary biology in cancer research, angiogenesis inhibitors, and modeling in vitro experiments.
I've also included a preprint on the pros/cons of small- and large-scale modeling techniques. To put it simply, small-scale models have gained acceptance by enabling ease of understanding and analysis, but biology tends neither to smallness or simplicity.
In case you missed it: here is .
-Jeffrey West
#MathOnco Publications
An optimal control approach for the treatment of solid tumors with angiogenesis inhibitors
Authors: Adam E. Glick, Antonio Mastroberardino
Applying tools from evolutionary biology to cancer research (book chapter)
Authors: Pedro M. Enriquez-Navas, Robert A. Gatenby
Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: implications for therapeutic targeting strategies
Authors: Seyed Peyman Shariatpanahi, Seyed Pooya Shariatpanahi, ..., Manuchehr Abedi-Valugerdi
Combining radiation with hyperthermia: a multiscale model informed by in vitro experiments
Authors: S. Bruningk, G. Powathil, ..., G. ter Haar
#MathOnco Preprints
Control and the analysis of cancer growth models
Authors: Allen R Tannenbaum, Tryphon Georgiou, Joseph Deasy, Larry Norton
Somatic maintenance alters selection acting on mutation rate
Authors: Andrii Rozhok, James DeGregori
Efficient pedigree recording for fast population genetics simulation
Authors: Jerome Kelleher, Kevin Thorton, Jaime Ashander, Peter Ralph
Complexity-aware simple modeling
Authors: Mariana Gomez-Schiavon, Hana El-Samad
Distribution-based measures of tumor heterogeneity are sensitive to mutation calling and lack strong clinical predictive power
Authors: Javad Noorbakhsh, Hyunsoo Kim, Sandeep Namburi, Jeff Chuang
#MathOnco blogs
Cancer's invasion equation
Siddhartha Mukherjee: "We’ve tended to focus on the cancer, but its host tissue—'soil,' rather than 'seed'—could help us predict the danger it poses."
Which cancers are survivable and why
Carlo Maley: "Cancer is not a death sentence; there is a great deal of difference between a prostate and a pancreatic cancer diagnosis, and even differences between subtypes of cancer within any particular organ. How can we understand this?"
#MathOnco Books
The Visual Display of Quantitative Information
So much of mathematical oncology requires top notch graphical display in order to best communicate information. This classic visualization book from Tufte goes into the history of graphics (including the first known graph) and best practices in stunning displays, page after page.
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