This Week in #MathOnco
This week in
Mathematical Oncology
February 8, 2018 ~ Issue 7
From the editor
Last week saw no math onco newsletter as I was busy attending the "Understanding Cancer through Evolutionary Game Theory" conference (follow the action at #cancerEGT on twitter) in Leiden.
As luck would have it, there has been a recent influx of game theory models in cancer to include in this week's issue: spatial vs non-spatial games, cancer dormancy / criticality as a game, and competition games in prostate cancer.
Following the eco-evo theme, I've included some trait fixation, epigenetic landscape, and niche construction preprints as well. These evolutionary ideas (and more) are also outlined in a James DeGregori's forthcoming book entitled Adaptive Oncogenesis, (now available for pre-order).
Enjoy,
-Jeffrey West
#MathOnco Publications
Spatial vs. non-spatial eco-evolutionary dynamics in a tumor growth model
Authors: Li You, Joel S. Brown, ..., Katerina Stankova
Cancer dormancy and criticality from a game theory perspective
Authors: Amy Wu, David Liao, ..., Robert Austin
Mathematical Modeling of the effects of tumor heterogeneity on the efficiency of radiation treatment schedule
Authors: Farinaz Forouzannia, Heiko Enderling, Mohammad Kohandel
Nanoparticle optimization for enhanced targeted anticancer drug delivery
Authors: Ibrahim M. Chamseddine and Michael Kokkolaras
#MathOnco Preprints
Competition and niche construction in a model of cancer metastasis
Authors: Jimmy Qian, Erol Akcay
The impact of tumor receptor heterogeneity on the response to anti-angiogenic cancer treatment
Authors: Ding Li, Stacey Finley
Capitalizing on competition: an evolutionary model of competitive release in metastastic castration resistant prostate cancer treatment
Authors: Jeffrey West, Yongqian Ma, Paul K Newton
Disentangling eco-evolutionary effects on trait fixation
Authors: Peter Czuppon, Chaitanya S Gokhale
Quantifying Waddington's epigenetic landscape: a comparison of single-cell potency measure
Authors: Jifan Shi, Andrew Teschendorff, ..., Tiejun Li
#MathOnco blogs
DNA seen through the eyes of a coder
Hat tip to Maxi Strobl for sending this along: the quirks and particulars of DNA information encoding, mutations, and more from the lens of a computer programmer. Perhaps a useful starting point to bridge the physical sciences - biology communication divide?
#MathOnco Books
Applying Graph Theory in Ecological Research
A broad intro into networks and graphs in ecology by Mark R. T. Dale: "Graph theory can be applied to ecological questions in many ways, and more insights can be gained by expanding the range of graph theoretical concepts applied to a specific system."
Adaptive Oncogenesis:
A New Understanding of How Cancer Evolves inside Us
James DeGregori's new cell biology book is now available for pre-order (to be released next month). The book "...corrects the fundamental attribution error that has focused cancer research on malignant cells and their genes. Adaptive oncogenesis, or ‘EcoOncogenesis,’ shows that the ecosystems surrounding cells are equally important, responsible for creating selection forces that speed or slow the evolution of cancer. "
Do you see something we missed? Click the submit button below to send us an idea for next week's issue.
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