#MathOnco Issue 91: cancer recurrence times, the "perturbome," genotype-phenotype, clonality, metastasis, and resistance
This week in
Math Oncology
Nov. 26, 2019 ~ Issue 91
From the editor
Hello!
Given that this week is a holiday for most, I'm sending this a bit earlier in the week. Today's topics include cancer recurrence times, the "perturbome," genotype-phenotype, clonality, metastasis, and resistance!
There is also a new job posting below, for a Quantitative Systems Pharmacology (QSP) Modeler.
Please enjoy!
-Jeffrey West
#MathOnco Publications
Cancer recurrence times from a branching process model
Authors: Stefano Avanzini,Tibor Antal
The mutator model with asymmetric transitions
Authors: David B. Saakian, Edgar Vardanyan
Individualized growth prediction of mice skin tumors with maximum likelihood estimators
Authors: Spyridon Patmanidisa, Alexandros C. Charalampidis, Ioannis Kordonis, Katerina Strati, Georgios D. Mitsis, George P. Papavassilopoulos
Cell-based simulations of biased epithelial lung growth
Authors: Anna Stopka, Marco Kokic and Dagmar Iber
Mapping the perturbome network of cellular perturbations
Authors: Michael Caldera, Felix Müller, Isabel Kaltenbrunner, Marco P. Licciardello, Charles-Hugues Lardeau, Stefan Kubicek & Jörg Menche
Using single nucleotide variations in single-cell RNA-seq to identify subpopulations and genotype-phenotype linkage
Authors: Olivier Poirion, Xun Zhu, Travers Ching & Lana X. Garmire
A mathematical model to study the effect of drug kinetics on the drug-induced resistance in tumor growth dynamics
Authors: TaLa, Wei Sun, Xiaoyang Zhao, Junping Zhang and Weisheng Guo
Dynamics of tumor growth: chemotherapy and integrative oncology
Authors: Tatiana R. Souza, Paulo F. A. Mancera, Rodney C. Bassanezi
#MathOnco Preprints
Minimal Barriers to Invasion During Human Colorectal Tumor Growth
Authors: Marc D. Ryser, Diego Mallo, Allison Hall, Timothy Hardman, Lorraine M. King, Inmaculada C. Sorribes, Carlo C. Maley, Jeffrey R. Marks, E. Shelley Hwang, Darryl Shibata
Pan-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases
Authors: Zheng Hu, Zan Li, Zhicheng Ma, Christina Curtis
Discrete and continuum models for the evolutionary and spatial dynamics of cancer: a very short introduction through two case studies
Authors: Tommaso Lorenzi, Fiona R. Macfarlane, Chiara Villa
Why scientists need to be better at data visualization
Betsy Mason: "The scientific literature is riddled with bad charts and graphs, leading to misunderstanding and worse. Avoiding design missteps can improve understanding of research."
#MathOnco - Book of the month
The Art of Theoretical Biology
Franziska Matthäus, Sebastian Matthäus, Sarah Harris, Thomas Hillen: "This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision."
Most clicked links of October
Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model
Key challenges facing data-driven multicellular systems biology
On measuring selection in cancer from subclonal mutation frequencies
Jobs
NEW: Quantitative Systems Pharmacology (QSP) Modeler - Cell Therapy (Dean Bottino)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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