#MathOnco Issue 92: universal cancer tasks & trade-offs; game theory; systems bio; machine learning; ecological models of cancer
This week in
Math Oncology
Dec. 5, 2019 ~ Issue 92
From the editor
Hello!
Today I've included a really interesting paper on universal cancer tasks & trade-offs, along with papers on game theory, systems bio, machine learning, and ecological models of cancer.
There is also another posting for Msc/Phd students studying pre-leukemic dynamics via Morgan Craig below.
Please enjoy!
-Jeffrey West
#MathOnco Publications
Tumor diversity and the trade-off between universal cancer tasks
Authors: Jean Hausser, Pablo Szekely, Noam Bar, Anat Zimmer, Hila Sheftel, Carlos Caldas & Uri Alon
Opportunities for improving cancer treatment using systems biology
Authors: Jason I. Griffiths, Adam L. Cohen, Veronica Jones, Ravi Salgia, Jeffrey T. Chang, Andrea H. Bild
Inferring growth and genetic evolution of tumors from genome sequences
Authors: VerenaKörber, ThomasHöfer
Evolutionary dynamics with game transitions
Authors: Qi Su, Alex McAvoy, Long Wang, Martin A. Nowak
Integrating machine learning and multiscale modeling—perspectives, challenges, and opportunities in the biological, biomedical, and behavioral sciences
Authors: Mark Alber, Adrian Buganza Tepole, William R. Cannon, Suvranu De, Salvador Dura-Bernal, Krishna Garikipati, George Karniadakis, William W. Lytton, Paris Perdikaris, Linda Petzold & Ellen Kuhl
Determinants of combination GM-CSF immunotherapy and oncolytic virotherapy success identified through in silico treatment personalization
Authors: Tyler Cassidy, Morgan Craig
Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression
Authors: Jani V. Anttila,Mikhail Shubin,Johannes Cairns,Florian Borse,Qingli Guo,Tommi Mononen,Ignacio Vázquez-García,Otto Pulkkinen,Ville Mustonen
#MathOnco Preprints
The ecology of cancer differentiation therapy I: non-spatial models
Authors: Ricard Solé, Guim Aguadé-Gorgorió
Malignant threats to humankind
James DeGregori and Niles Eldredge: "Almost all of us have experienced the devastating effects of cancer, either by our own battles with the disease or through its impacts on our friends and family. In fact, 40% of people in industrialized countries develop cancer, and about half will die of their disease. It is also widely accepted (with notable exceptions) that species diversity and environments on Earth are under serious threat, due both to human-caused climate change and habitat destruction. The Earth is currently in the midst of the 6th Extinction, with massive losses in species diversity resulting from human-caused habitat destruction, climate change, and direct killing of species. But what do these tragic conditions have in common, and how can one inform the other?"
#MathOnco - Book of the month
The Art of Theoretical Biology
Franziska Matthäus, Sebastian Matthäus, Sarah Harris, Thomas Hillen: "This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision."
Most clicked links of Oct/Nov
Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model
Dynamics of tumor growth: chemotherapy and integrative oncology
Key challenges facing data-driven multicellular systems biology
On measuring selection in cancer from subclonal mutation frequencies
Jobs
NEW: Pre-leukemic Dynamics – MSc or PhD Studentship (Morgan Craig)
NEW: Quantitative Systems Pharmacology (QSP) Modeler - Cell Therapy (Dean Bottino)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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