#MathOnco Issue 97: virtual clinical trials, immuno space-time dynamics, Muller's ratchet, objective functions, and more.
This week in
Math Oncology
Jan. 9, 2019 ~ Issue 97
From the editor
Hello!
I hope that 2020 is off to a running start for everyone! Today's issue contains manuscripts on virtual clinical trials, immuno space-time dynamics, Muller's ratchet, and objective functions. Scroll down for more.
The job openings continue! It's as good a time as ever to get into (or continue in) math onco. Scroll down for PhD (Fabian Spill) and Postdoc (Russell Rockne) opportunities.
Please enjoy!
-Jeffrey West
#MathOnco Publications
Immunotherapeutic Transport Oncophysics: Space, Time, and Immune Activation in Cancer
Authors: Sara Nizzero, Haifa Shen, Mauro Ferrari, Bruna Corradetti
Virtual clinical trials identify effective combination therapies in ovarian cancer
Authors: Emilia Kozłowska, Tuulia Vallius, Johanna Hynninen, Sakari Hietanen, Anniina Färkkilä & Sampsa Hautaniemi
Forecasting tumor and vasculature response dynamics to radiation therapy via image based mathematical modeling
Authors: David A. Hormuth II, Angela M. Jarrett & Thomas E. Yankeelov
Can postfertile life stages evolve as an anticancer mechanism?
Authors: Frédéric Thomas ,Mathieu Giraudeau,François Renaud,Beata Ujvari,Benjamin Roche,Pascal Pujol,Michel Raymond,Jean-François Lemaitre ,Alexandra Alvergne
#MathOnco Preprints
The spatial Muller’s ratchet: surfing of deleterious mutations during range expansion
Authors: Félix Foutel-Rodier, Alison Etheridge
Biological Regulatory Networks are Minimally Frustrated
Authors: Shubham Tripathi, David A. Kessler, Herbert Levine
Solving multi-objective functions for cancer treatment by using Metaheuristic Algorithms
Authors: Farid Heydarpoor, Seyed Mehdi Karbassi, Narges Bidabadi, Narges Bidabadi, M. J. Ebadi
A New Approach to Cancer Treatment Draws Lessons From Darwin
Brianna Abbott: "Called adaptive therapy, the treatment stems from the recognition that cancerous cells, just like other forms of life, mutate and evolve in response to a changing environment. Traditional cancer treatment—continuously bombarding cancer cells with drugs—can encourage drug-resistant cells to multiply, eventually creating an untreatable tumor."
Most clicked links of December
Tumor diversity and the trade-off between universal cancer tasks
Opportunities for improving cancer treatment using systems biology
Inferring growth and genetic evolution of tumors from genome sequences
Jobs
NEW: Postdoctoral Fellow in Mathematical Oncology (Russell Rockne)
NEW: PhD in Dynamic interplay of cell shape and tumour evolution (Fabian Spill)
NEW: PhD in Dynamics of Mitochondria in Health and Disease (Fabian Spill)
NEW: PhD in Mathematical Modelling of Cancer-Cell Transmigration Through Blood Vessels (Fabian Spill)
New: Postdoc: University of Birmingham - Institute of Metabolism and Systems Research
Pre-leukemic Dynamics – MSc or PhD Studentship (Morgan Craig)
Quantitative Systems Pharmacology (QSP) Modeler - Cell Therapy (Dean Bottino)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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