#MathOnco Issue 17: special issue Math Bio Bulletin! Combination therapy, evolution of resistance, synergism/antagonism, virtual patients
This week in
Mathematical Oncology
May 2, 2018 ~ Issue 17
From the editor
One very exciting update in the world of #mathonco occurred this week: the release of a special issue of the Bulletin of Mathematical Biology on mathematical oncology. Click the image below to browse the edition. In other news, publications in combination therapy in relation to resistance evolution and an interesting non-cancer model on resistance were released, with some interesting preprints on evolving networks, virtual patients, and subclonal reconstruction standards.
Enjoy,
-Jeffrey West
#MathOnco Publications
Click here to see full issue
Bulletin of Mathematical Biology: Mathematical Oncology Special Issue
Mathematical Oncology
Authors: Alexander R. A. Anderson, Philip K. Maini
Combination therapy and the evolution of resistance: the theoretical merits of synergism and antagonism in cancer
Authors: Elyzia C. Saputra, Lu Huang, Yihui Chen, Lisa Tucker-Kellogg
Beyond dose: Pulsed antibiotic treatment schedules can maintain individual benefit while reducing resistance
Authors: Christopher M. Baker, Matthew J. Ferrari, Katriona Shea
#MathOnco Preprints
Replicative cellular age distributions in compartmentalised tissues
Authors: Marvin A. Boettcher, Benjamin Werner, David Dingli, Arne Traulsen
Comparison of single gene and module-based methods for modeling gene regulatory networks
Authors: Mikel Hernaez, Olivier Gevaert
Revese engineered virtual patient populations as surrogates for real patient-level data
Authors: Francis J Alenghat
Collapse and rescue of cooperation in evolving dynamic networks
Authors: Erol Akcay
Creating standards for evaluating tumor subclonal reconstruction
Authors: Paul C Boutros, Adriana Salcedo, Maxime Tarabichi, ..., Peter Van Loo, DREAM SMC-Het Participants
#MathOnco News
Cells talk and help one another via tiny tube networks
Viviane Callier: " Research teams have discovered that "tunneling nanotubes " (TNTs) transfer all kinds of cargo beyond microRNAs, including messenger RNAs, proteins, viruses and even whole organelles, such as lysosomes and mitochondria. Cancer cells are often stressed — these rapidly dividing cells survive hypoxia, nutrient stress, oxidative stress and more. So it’s not surprising that they induce TNTs. "
#MathOnco Books
Science and human values
A collection of three essays based on three lectures the author gave as Carnegie Professor at MIT in the early 1950's. The first essay is profoundly relevant to the exercise of math modeling. He argues that science (as well as art) is a creative act of the human mind, and proceeds to outline a short overview of a philosophy of science that many in the creative enterprise of math modeling may find useful.
Do you see something we missed? Click the submit button below to send us an idea for next week's issue.
The #MathOnco newsletter is maintained by @jeffreyjizzle. If you were forwarded this email, subscribe for free here to get it delivered every week.