#MathOnco Issue 105: glioblastoma models, drug synergistic effects, the cancer microbiome, organoid dynamics
This week in
Math Oncology
Mar. 5, 2020 ~ Issue 105
From the editor
Hello!
Today's issue of "This week in Mathematical Oncology" includes glioblastoma models, drug synergistic effects, the cancer microbiome, organoid dynamics, and more!
Enjoy!
-Jeffrey West
#MathOnco Publications
From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response
Authors: Jill A. Gallaher, Susan C. Massey, Andrea Hawkins-Daarud, Sonal S. Noticewala, ..., Orlando Gil, Kristin R. Swanson, Peter Canoll, Alexander R. A. Anderson
Charting the Fragmented Landscape of Drug Synergy
Authors: Christian T.Meyer, David J.Wooten, Carlos F.Lopez, VitoQuaranta
The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View
Authors: Joao B. Xavier, Vincent B. Young, Joseph Skufca, Fiona Ginty, ..., Andrew Y. Koh, Michael Yu, Libusha Kelly, Jennifer A. Wargo
OrgDyn: Feature and model based characterization of spatial and temporal organoid dynamics
Authors: Zaki Hasnain, Andrew K Fraser, Dan Georgess, Alex Choi, Paul Macklin, Joel S Bader, Shelly R Peyton, Andrew J Ewald, Paul K Newton
Mathematical oncology and it’s application in non melanoma skin cancer – A primer for radiation oncology professionals
Authors: Noel J. Aherne, Andrew Dhawan, Jacob G.Scott, Heiko Enderling
Genetic heterogeneity and evolutionary history of high-grade ovarian carcinoma and matched distant metastases
Authors: Tariq Masoodi, Sarah Siraj, Abdul K. Siraj, Saud Azam, ..., Osama AlOmar, Ismail A. Al-Badawi, Fowzan S. Alkuraya, Khawla S. Al-Kuraya
Artificial intelligence in cancer therapy
Authors: Dean Ho
#MathOnco Preprints
Tissue size controls patterns of cell proliferation and migration in freely-expanding epithelia
Authors: Matthew A Heinrich, Julienne LaChance, Tom J. Zajdel, Ricard Alert, Andrej Kosmrlj, Daniel J. Cohen
High school Internship Program in Integrated Mathematical Oncology (HIP IMO) – five-year experience at Moffitt Cancer Center
Authors: Heiko Enderling, Philipp M. Altrock, Noemi Andor, David Basanta, Joel S. Brown, Robert A. Gatenby, Andriy Marusyk, Katarzyna A. Rejniak, Ariosto Silva, Alexander R.A. Anderson
Why we can’t cure cancer with a moonshot
William G. Kaelin Jr.: "Treating early-stage science like engineering, however, is shortsighted and counterproductive. Early-stage science is often dominated by creative individuals who are allowed to follow their curiosity and to go where their scientific discoveries take them. Prematurely forcing scientists into teams with predetermined deliverables risks creating a herd mentality and tunnel vision. Better to have 10 scientists going in different directions in hopes that one of them actually discovers something."
#MathOnco - Book of the month
Tales of Impossibility: The 2000-Year Quest to Solve the Mathematical Problems of Antiquity
David S Richeson: "Tales of Impossibility recounts the intriguing story of the so-called problems of antiquity, four of the most famous and studied questions in the history of mathematics. First posed by the ancient Greeks, these compass and straightedge problems—squaring the circle, trisecting an angle, doubling the cube, and inscribing regular polygons in a circle—have served as ever-present muses for mathematicians for more than two millennia. David Richeson follows the trail of these problems to show that ultimately, their proofs—demonstrating the impossibility of solving them using only a compass and straightedge—depended upon and resulted in the growth of mathematics."
Jobs
NEW: Computational Approaches to Breast Cancer Evolution - Postdoc (Marc Ryser)
Postdoctoral Fellow in Mathematical Oncology (Russell Rockne)
Pre-leukemic Dynamics – MSc or PhD Studentship (Morgan Craig)
Quantitative Systems Pharmacology (QSP) Modeler - Cell Therapy (Dean Bottino)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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