#MathOnco Issue 114: optimal treatment models, phenotypic diversity, tumor-parenchyma biomechanics, and evo-eco dynamics.
This week in
Math Oncology
May 7, 2020 ~ Issue 114
From the editor
Dear Readers,
Today's issue has publications on optimal treatment models, phenotypic diversity, tumor-parenchyma biomechanics, and evo-eco dynamics.
I'm reposting two links: first, the free textbooks from Spring (a great resource!), and the book, "The Art of Theoretical Biology," which is officially released.
Happy Thursday,
-Jeffrey West
#MathOnco Publications
Optimal treatment strategies for delayed cancer-immune system with multiple therapeutic approach
Authors: Parthasakha Das, Samhita Das, Ranjit Kumar Upadhyay, Pritha Das
Assessing Cell Activities rather than Identities to Interpret Intra-Tumor Phenotypic Diversity and Its Dynamics
Authors: Laloé Monteiro, Lydie Da Silva, Boris Lipinski, Frédérique Fauvet, Arnaud Vigneron, Alain Puisieux, Pierre Martinez
Mathematical Model Predicts Effective Strategies to Inhibit VEGF-eNOS Signaling
Authors: Qianhui Wu, Stacey D. Finley
Improved progression-free survival with continuous compared to intermittent dosing with dabrafenib and trametinib in patients with BRAF mutated melanoma (Clinical Trial)
Authors: Alain Algazi, Megan Othus, Adil Daud, Roger Lo, ..., Luke Dreisbach, James Moon, Kenneth Grossman, Antoni Ribas
#MathOnco Preprints
Retrospective analysis of a fatal dose-finding trial
Authors: David C. Norris
Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach
Authors: Yafei Wang, Erik Brodin, Kenichiro Nishii, Hermann B Frieboes, Shannon Mumenthaler, Jessica L Sparks, Paul Macklin
Evolution is exponentially more powerful with frequency-dependent selection
Authors: Artem Kaznatcheev
All that’s fit to preprint (Editorial)
Nature Biotechnology: "COVID-19 has reinforced the importance of preprints as an indispensable means for rapid research dissemination. The uptake of preprints during the COVID-19 pandemic has been nothing short of remarkable. In April, the clinical preprint repository medRxiv published between 50 and 100 SARS-CoV-2-related posts daily. ... In the longer term, it also may prove a watershed moment, signaling the arrival of preprints as a legitimate complement to peer-reviewed journals, broadening their acceptance among a wider community of researchers, and accelerating their integration into journal publishing workflows."
https://mathseminars.org/
mathseminars.org: a listing of research seminars and conferences. The front page lists upcoming talks. You can filter them by subject, topic, or language to tailor them to your interests. After registering, you can export selected series and talks to your own calendar (e.g., Google calendar, Outlook or iCal). When you subscribe to a series, new talks will be pushed to your calendar automatically.
Free textbooks during Covid-19
Springer: As a response to Covid-19, Springer Link is offering several hundred books (in PDF format) for FREE. Relevant titles include:
Stability and Control of Linear Systems
Applied Bioinformatics
Neural Networks and Deep Learning
The A-Z of the PhD Trajectory
Data Science and Predictive Analytics
... and more!
#MathOnco - Book of the month
The Art of Theoretical Biology
Franziska Matthäus, Sebastian Matthäus, Sarah Harris, Thomas Hillen: "This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision."
Jobs
Computational Approaches to Breast Cancer Evolution - Postdoc (Marc Ryser)
Pre-leukemic Dynamics – MSc or PhD Studentship (Morgan Craig)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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