#MathOnco Issue 27: oncolytic virotherapy, adaptive plasticity, estimating heterogeneity/fitness, elementary flux modes
This week in
Mathematical Oncology
July 19, 2018 ~ Issue 27
From the editor
I hope to see many of you at ECMTB next week in Portugal -- if we haven't met please come say hi! Meanwhile, please enjoy this week's collection of articles which includes preprints on oncolytic virotherapy, adaptive plasticity, estimating heterogeneity/fitness, as well a preprint on "elementary flux modes" in (non-cancer) metabolic networks that may be of interest.
-Jeffrey West
#MathOnco Publications
Cancer-causing somatic mutations: they are neither necessary nor sufficient
Authors: Carlos Sonnenschein, Ana M. Soto
Predictive Modeling of Neuroblastoma Growth Dynamics in Xenograft Model After Bevacizumab Anti-VEGF Therapy
Authors: Yixuan He, Anita Kodali, Dorothy I. Wallace
#MathOnco Preprints
Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis
Authors: Joseph Malinzi, Rachid Ouifki, Amina Eladdadi, Delfim F. M. Torres, K. A. Jane White
Efficient pedigree recording for fast population genetics simulation
Authors: Jerome Kelleher, Kevin Thornton, Jaime Ashander, Peter Ralph
How adaptive plasticity evolves when selected against
Authors: Alfredo Rago, Kostas Kouvaris, Tobias Uller, Richard A Watson
Estimating heterogeneous treatment effects by balancing heterogeneity and fitness
Authors: Weijia Zhang, Thuc Le, Lin Liu, Jiuyong Li
A simple and flexible computational framework for inferring sources of heterogeneity from single-cell dynamics
Authors: Lekshmi Dharmarajan, Hans-Michael Kaltenbach, Fabian Rudolf, Joerg Stelling
Maximal growth rate requires minimal metabolic complexity
Authors: Daan Hugo de Groot, Coco van Boxtel, Robert Planqué, Frank J. Bruggeman, Bas Teusink
#MathOnco News
What Can Odd, Interesting Medical Case Studies Teach Us?
Siddhartha Mukherjee: "These days, we typically write observational reports on single patients to teach students about the past: This is how this medical mystery was cracked. But perhaps we might revive the case study that looks to the future: I cannot diagnose this condition, or explain it away, but I will record it in its fullest, richest form for another generation of medical students to puzzle over."
#MathOnco - Book of the month
Letters to a Young Scientist
Edward O. Wilson: The Pulitzer Prize–winning biologist imparts the wisdom of his storied career to the next generation by threading twenty-one letters with autobiographical anecdotes that illuminate his motivations for becoming a biologist." With section titles like "The Creative Process" or "What is science?" or "Theory and the Big Picture," this emerging classic is sure to interest the scientist young or old.
#MathOnco - Best of last month
Most clicked links of June
Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model
Passenger mutations can accelerate tumour suppressor gene inactivation in cancer evolution
Cancer as a Social Dysfunction - Why Cancer Research Needs New Thinking
Do you see something we missed? Click the submit button below to send us an idea for next week's issue.
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