#MathOnco Issue 28: are there theoretical "results?" ; mechanical and systems bio, metastatic castrate resistant prostate cancer
This week in
Mathematical Oncology
July 26, 2018 ~ Issue 28
From the editor
Twitter was abuzz this week with the nicely titled eLife review called "Are theoretical results ‘Results’?" -- answering, of course, with a resounding "yes." See that and more below.
In other news, I was reviewing some statistics and information about this newsletter. Did you know that we have 250 subscribers, sent around 230 publications/preprints, and delivered over 3,800 emails? I hope this newsletter continues to serve as a community building exercise: reaching the right audience with the right science. Keep the great science coming,
-Jeffrey West
#MathOnco Publications
Point of View: Are theoretical results ‘Results’?
Authors: Raymond E Goldstein
Mechanical and Systems Biology of Cancer
Authors: Fabian Spill, Chris Bakal, Michael Mak
A Two-Phenotype Model of Immune Evasion by Cancer Cells
Authors: Péter Bayer, Joel S.Brown, Kateřina Staňková
What does not kill a tumour may make it stronger: In silico insights into chemotherapeutic drug resistance
Authors: Sara Hamis Perumal Nithiarasu Gibin G.Powathil
A two‐drug combination simulation study for metastatic castrate resistant prostate cancer
Authors: Alex Root, H. Alexander Ebhardt
Capitalizing on Competition: An Evolutionary Model of Competitive Release in Metastatic Castration Resistant Prostate Cancer Treatment
Authors: Jeffrey West, Yongqian Ma, Paul K Newton
#MathOnco Preprints
Towards personalized computer simulation of breast cancer treatment: a multi-scale pharmacokinetic and pharmacodynamic model informed by multi-type patient data
Authors: Xiaoran Lai, Oliver Geier, Thomas Fleischer, Oeystein Garred, Elin Faye Borgen, ..., Arnoldo Frigessi
Balance of Mechanical Forces Drives Endothelial Gap Formation and May Facilitate Cancer and Immune-Cell Extravasation
Authors: Jorge Escribano, Michelle Chen, Emad Moeendarbary, Xuan Cao, Vivek Shenoy, Jose Manuel Garcia-Aznar, Roger Kamm, Fabian Spill
#MathOnco News
Cells Talk and Help One Another via Tiny Tube Networks
Viviane Callier: "Breast cancer cells in culture form tubelike interconnections. ... Payloads of molecules (inside blue circles) can be seen moving along these membranous nanotubes and microtubes, illustrating how they might be transmitted to a cell in need of them. Such connections may help cancer cells share their resistance to therapeutic drugs."
#MathOnco - Book of the month
Letters to a Young Scientist
Edward O. Wilson: The Pulitzer Prize–winning biologist imparts the wisdom of his storied career to the next generation by threading twenty-one letters with autobiographical anecdotes that illuminate his motivations for becoming a biologist." With section titles like "The Creative Process" or "What is science?" or "Theory and the Big Picture," this emerging classic is sure to interest the scientist young or old.
#MathOnco - Best of last month
Most clicked links of June
Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model
Passenger mutations can accelerate tumour suppressor gene inactivation in cancer evolution
Cancer as a Social Dysfunction - Why Cancer Research Needs New Thinking
Do you see something we missed? Click the submit button below to send us an idea for next week's issue.
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