#MathOnco Issue 29: somatic event timing, causation in cancer, models of overtreatment, predictive systems biology models
This week in
Mathematical Oncology
Aug. 2, 2018 ~ Issue 29
From the editor
Hello all,
Another exciting week of updates in the math oncology field brings with it articles in somatic event timing, causation in cancer, models of overtreatment, and a general treatise on building systems biology models to make predictions.
Every week I get questions about the newsletter (i.e. "how long does it take you?" and "how many people are subscribed?") -- so I've put together a blog post chronicling the journy with some statistics of our community's habits. Read it here.
-Jeffrey West
#MathOnco Publications
Timing somatic events in the evolution of cancer
Authors: Clemency Jolly, Peter Van Loo
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer
Authors: Tomoko Saito, Atsushi Niida, ..., Koshi Mimori
Rethinking Causation in Cancer with Evolutionary Developmental Biology
Authors: Katherine E. Liu
Mathematical Models for Tumor Growth and the Reduction of Overtreatment
Authors: Berdine L. Heesterman, John-Melle Bokhorst, Lisa M. H. de Pont, ..., Jeroen C. Jansen
A structural methodology for modeling immune-tumor interactions including pro- and anti-tumor factors for clinical applications
Authors: AbazarArabameri, Davud Asemani, Jamshid Hajati
#MathOnco Preprints
Cancer evolution in a changing microenvironment
Authors: Xiaowei Jiang, Ian P.M. Tomlinson
Constructing predictive cancer systems biology models
Authors: Jennifer A Rohrs, Sahak Z Makaryan, Stacey D Finley
Modelling bistable tumour population dynamics to design effective treatment strategies
Authors: Andrei R. Akhmetzhanov, Jong Wook Kim, Ryan Sullivan, Robert A. Beckman, Pablo Tamayo, Chen-Hsiang Yeang
#MathOnco News
From code to cure
David J Craig: "Armed with enormous amounts of clinical data, teams of computer scientists, statisticians, and physicians are rewriting the rules of medical research."
#MathOnco - Book of the month
Ecology and Evolution of Cancer
B. Ujvari, B. Roche, F. Thomas: "Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field."
#MathOnco - Best of last month
Most clicked links of July
Cancer-causing somatic mutations: they are neither necessary nor sufficient
Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow
Mechanistic models versus machine learning, a fight worth fighting for the biological community?
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