#MathOnco Issue 44: game theory in cancer; adaptive therapy; mutational interactions; evolutionary dynamics
This week in
Mathematical Oncology
Nov. 29, 2018 ~ Issue 44
From the editor
Hello #MathOnco readers,
This week's issue has all my favorite topics: game theory in cancer, adaptive therapy, and evolutionary dynamics, and even some discussion on interdisciplinary science!
Also, I'd like to draw your attention to a new Python data visualization library called Chartify. It was created out of Spotify Labs in an attempt to create more intuitive Python chart creation tools. Check out the extensive list of examples here.
Hope you all had a wonderful Thanksgiving weekend,
-Jeffrey West
#MathOnco Publications
Evolutionary dynamics of residual disease in human glioblastoma
Authors: I Spiteri G Caravagna G D Cresswell A Vatsiou D Nichol A Acar L Ermini K Chkhaidze B Werner R Mair E Brognaro R G W Verhaak G Sanguinetti S G M Piccirillo C Watts A Sottoriva
Cooperation among cancer cells: applying game theory to cancer
Authors: Marco Archetti & Kenneth J. Pienta
Mutational interactions define novel cancer subgroups
Authors: Jack Kuipers, Thomas Thurnherr, Giusi Moffa, Polina Suter, Jonas Behr, Ryan Goosen, Gerhard Christofori & Niko Beerenwinkel
#MathOnco Preprints
Towards multi-drug adaptive therapy
Authors: Jeffrey West, Li You, Joel Brown, Paul K Newton, Alexander RA Anderson
Computational modeling reveals dynamics of brain metastasis in non-small cell lung cancer and provides a tool for personalized therapy
Authors: Mariia Bilous, Cindy Serdjebi, Arnaud Boyer, Pascale Tomasini, Claudia Pouypoudat, Dominique Barbolosi, Fabrice Barlési, François Chomy, Sébastien Benzekry
In Silico Implementation of Paradigmatic Evolutionary Principles in Therapy Design: Resistant Cells as Prospective Inhibitors of Non-Efficient Therapies?
Authors: Branislav Brutovsky, Denis Horvath
Every which way? On predicting tumor evolution using cancer progression models
Authors: Ramon Diaz-Uriarte, Claudia Vasallo
Moving beyond P values: Everyday data analysis with estimation plots
Authors: Joses Ho, Tayfun Tumkaya, Sameer Aryal, Hyungwon Choi, Adam Claridge-Chang
#MathOnco News
The Noble Eightfold Path to Mathematical Biology
Artem Kaznatcheev: Is "expecting both novel mathematics and novel biology from an exploration in an interdisciplinary field like mathematical oncology is asking for too much?"
This intriguing blog post offers a response: "science is about keeping as many parameters fixed as possible and trying to vary only one at a time. I am not sure if I agree. I think that if we follow the Noble Eightfold Path then we can achieve both biology and mathematical novelty.”
#MathOnco - Book of the month
I Contain Multitudes
Yong: "In I Contain Multitudes, Yong synthesizes literally hundreds and hundreds of papers, but he never overwhelms you with the science. He just keeps imparting one surprising, fascinating insight after the next. I Contain Multitudes is science journalism at its best.” -Bill Gates
Most clicked links of October
Ten simple rules for developing good reading habits during graduate school and beyond
From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology
Evolution of Metastases in Space and Time under Immune Selection
Nonidentifiability in Model Calibration and Implications for Medical Decision Making
Jobs
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