#MathOnco Issue 46: the MathOnco 1 year anniversary
This week in
Mathematical Oncology
Dec. 13, 2018 ~ Issue 46
From the editor
Hello #MathOnco readers,
With great pleasure, I can wish a "happy anniversary" to the #MathOnco newsletter this week.
On December 18, 2017 I authored the first #MathOnco newsletter. Since then, I've collectively sent 8,925 emails over 46 issues. I'm impressed by your insatiable appetite for math oncology: you clicked on 5,791 links over the course of a year. And, it's truly a worldwide field, evidenced by the heat map of our 319 subscribers below:
It's an honor to show up in your inbox every week. What will the next year hold? Only time will tell...
-Jeffrey West
#MathOnco Publications
The evolutionary landscape of colorectal tumorigenesis
Authors: William Cross, Michal Kovac, Ville Mustonen, Daniel Temko, ..., Andrea Sottoriva, Simon J. Leedham, Trevor A. Graham, Ian P. M. Tomlinson
Macroscopic Cerebral Tumor Growth Modelling from Medical Images: A Review
Authors: Ahmed Elazab, Yousry M Abdulazeem, Ahmed M. Anter, Baiying Lei
Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors
Authors: Andrew Dhawan, Jacob G. Scott, Adrian L. Harris & Francesca M. Buffa
Design Optimization of Tumor Vasculature-Bound Nanoparticles
Authors: Ibrahim M. Chamseddine, Hermann B. Frieboes & Michael Kokkolaras
#MathOnco Preprints
Relating evolutionary selection and mutant clonal dynamics in normal epithelia
Authors: Michael W J Hall, Philip H Jones, Benjamin A Hall
Tumor pre-conditioning of draining lymph node stroma by lactic acid
Authors: Angela Riedel, Jonathan Swietlik, David Shorthouse, Lisa Haas, Tim Young, Ana S H Costa, Sarah Davidson, Luisa Pedro, Thordur Oskarsson, Benjamin A Hall, Christian Frezza, Jacqueline Shields
Optimizing adaptive cancer therapy: dynamic programming and evolutionary game theory
Authors: Mark Gluzman, Jacob G. Scott, Alexander Vladimirsky
Share, but unequally: A plausible mechanism for emergence and maintenance of intratumor heterogeneity
Authors: Xin Li, D. Thirumalai
NeoPredPipe: High-Throughput Neoantigen Prediction and Recognition Potential Pipeline
Authors: Ryan O. Schenck, Eszter Lakatos, Chandler Gatenbee, Trevor A. Graham, Alexander R.A. Anderson
#MathOnco News
Just say no to “de novo resistance”
Rob Noble: "Due to these different interpretations, the cancer and infectious disease research literature abounds with papers using “de novo resistance” to mean either pre-existing resistance [e.g. 1-5] or non-pre-existing resistance [e.g. 6-9]. And as evolutionary biology increasingly addresses medical questions, this particular bit of jargon is apt to confuse more than it clarifies."
#MathOnco - Book of the month
Cancer: The Evolutionary Legacy
Mel Greaves: Placing cancer in its evolutionary context, Greaves argues that "we can best answer the big questions about cancer by looking through a Darwinian lens. Drawing on both ancient and more modern evolutionary legacies, he shows how human development has changed the rules of evolutionary games, trapping us in a nature-nurture mismatch."
Most clicked links of November
A mathematical framework for modelling the metastatic spread of cancer
Evolutionary dynamics of residual disease in human glioblastoma
Cooperation among cancer cells: applying game theory to cancer
Jobs
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