#MathOnco Issue 43: fitness trade-offs in tumors; dormancy mechanisms; tyrosine kinase inhibition; framework for metastatic spreading
This week in
Mathematical Oncology
Nov. 15, 2018 ~ Issue 43
From the editor
What an exciting week in math onco, it took me no time at all to collect these eight relevant articles for the week. We have models on topics including such as fitness trade-offs in tumors, dormancy, tyrosine kinase inhibition, and a very nice framework for metastatic spreading.
Enjoy,
-Jeffrey West
#MathOnco Publications
Reduced Tyrosine Kinase Inhibitor Dose Is Predicted To Be As Effective As Standard Dose In Chronic Myeloid Leukemia: A Simulation Study Based On Phase III Trial Data
Authors: Artur C. Fassoni, Christoph Baldow, Ingo Roeder, Ingmar Glauche
Life History Trade-Offs in Tumors
Authors: Amy M. Boddy, Weini Huang, Athena Aktipis
The Equivalence Induced by Unifying Fitness Mappings in Frequency-Dependent Moran Process
Authors: Feng Huang, Xiaojie Chen, Long Wang
Dormant, quiescent, tolerant and persister cells: four synonyms for the same target in cancer
Authors: François M. Vallette, Christophe Olivier, Frédéric Lézot, ..., Dominique Heymann
#MathOnco Preprints
Spatio-Genetic and Phenotypic Modelling Elucidates Resistance and Re-Sensitisation to Treatment in Heterogeneous Melanoma
Authors: Arran Hodgkinson, Laurent Le Cam, Dumitru Trucu, Ovidiu Radulescu
A mathematical framework for modelling the metastatic spread of cancer
Authors: Linnea Christin Franssen, Tommaso Lorenzi, Andrew Felix Burgess, Mark AJ Chaplain
Proliferation Saturation Index in an adaptive Bayesian approach to predict patient-specific radiotherapy responses
Authors: Enakshi D. Sunassee, Dean Tan, Tianlin Ji, Renee Brady, Eduardo G. Moros, Jimmy J. Caudell, Slav Yartsev, Heiko Enderling
Exploring and mapping the universe of evolutionary graphs
Authors: Marius Möller, Laura Hindersin, Arne Traulsen
#MathOnco News
Neighbourhood deaths cause a switch in cancer subtype
Eli Pikarsky: “Seehawer et al. reveal that the same type of cell can give rise to different types of cancer depending on the sort of cell death that occurs nearby in the tumour microenvironment. This suggests that nearby injury or damage can affect the identity of a cancer.”
#MathOnco - Book of the month
I Contain Multitudes
Yong: "In I Contain Multitudes, Yong synthesizes literally hundreds and hundreds of papers, but he never overwhelms you with the science. He just keeps imparting one surprising, fascinating insight after the next. I Contain Multitudes is science journalism at its best.” -Bill Gates
Most clicked links of September
Mathematical modeling predicts response to chemotherapy and drug combinations in ovarian cancer
Topography of cancer-associated immune cells in human solid tumors
Game Theoretical Model of Cancer Dynamics with Four Cell Phenotypes
Jobs
Do you see something we missed? Reply to this email to send us an idea for next week's issue.
The #MathOnco newsletter is maintained by Jeffrey West.
If you were forwarded this email, subscribe for free here to get it delivered every week.