#MathOnco Issue 123: simultaneous selection pressures, a phase-field prostate model, systems immunology, EGT control theory, genotype-phenotype
This week in
Math Oncology
July 16, 2020 ~ Issue 123
From the editor
Hello everyone!
Today's issue includes manuscripts on simultaneous selection pressures, a phase-field prostate model, systems immunology, cancer initiation, EGT control theory, and genotype-phenotype maps. There's also a new postdoc position in computational immunology, indicated below.
Enjoy,
-Jeffrey West
#MathOnco Publications
Application of Simultaneous Selective Pressures Slows Adaptation
Authors: Lauren M.F. Merlo, Kathleen Sprouffske, Taylor C. Howard, Kristin L. Gardiner, Aleah F. Caulin, Steven M. Blum, Perry Evans, Antonio Bedalov, Paul D. Sniegowski, Carlo C. Maley
In silico modelling of cancer nanomedicine, across scales and transport barriers
Authors: Namid R. Stillman, Marina Kovacevic, Igor Balaz, Sabine Hauert
Mathematical analysis and simulation study of a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects
Authors: Pierluigi Colli, Hector Gomez, Guillermo Lorenzo, Gabriela Marinoschi, Alessandro Reali, Elisabetta Rocca
Cancer systems immunology
Authors: Nathan E Reticker-Flynn, Edgar G Engleman
#MathOnco Preprints
Spread of premalignant mutant clones and cancer initiation in multilayered tissue
Authors: Jasmine Foo, Einar Bjarki Gunnarsson, Kevin Leder, Kathleen Storey
SITH: an R package for visualizing and analyzing a spatial model of intratumor heterogeneity
Authors: Phillip B. Nicol, Dániel L. Barabási, Amir Asiaee, Kevin R. Coombes
A genotype-phenotype-fitness map reveals local modularity and global pleiotropy of adaptation
Authors: Grant Kinsler, Kerry Geiler-Samerotte, Dmitri Petrov
Maximizing cooperation in the prisoner's dilemma evolutionary game via optimal control
Authors: Paul K. Newton, Yongqian Ma
Optimal control of cytotoxic and antiangiogenic therapies on prostate cancer growth
Authors: Pierluigi Colli, Hector Gomez, Guillermo Lorenzo, Gabriela Marinoschi, Alessandro Reali, Elisabetta Rocca
Virtual Seminars
1. Virtual Seminar Series on Modeling Biocomplexity:
Cancer Invasion and Progression Series
Next talk: Bob Gatenby (Moffitt Cancer Centre, Tampa, Florida)
"Evolution-based models to control and cure metastatic cancers"
July 22, 2020 at 5:00pm CEST
2. Mathematical and Computational Biology Seminar Series:
Bioinformatics, Computational Biology, General Mathematics
Next talk: Santiago Schnell (University of Michigan)
"Developing models for the accurate measurement of enzyme kinetic parameters"
July 27, 2020 at 11:00am EST
#MathOnco - Book of the month
The Cheating Cell
Athena Aktipis: "When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments."
Jobs
NEW: Postdoctoral Research Position in Computational Immunology (Sylvain Cussat-Blanc)
Postdoc Position - TKI treatments in lung cancer (David Basanta)
Research Associate, Postdoc, and Research Faculty positions – Mathematical Oncology (Russ Rockne)
Systems Biology Modeler Positions in Biopharma Consulting Company (Helen Moore)
Computational Approaches to Breast Cancer Evolution - Postdoc (Marc Ryser)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
Do you see something we missed? Reply to this email to send us an idea for next week's issue.
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