#MathOnco Issue 65: predicting tumor evolution; personalized cancer treatment schedules
This week in
Math Oncology
May 9, 2019 ~ Issue 65
From the editor
Dear #MathOnco community,
Two trends that are continually coming into the focus of the math oncology community are 1) predicting/steering tumor evolution and 2) personalized cancer treatment schedules. This issue contains both of these topics and more!
Enjoy,
-Jeffrey West
#MathOnco Publications
A generalized theory of age-dependent carcinogenesis
Authors: Andrii Rozhok, James DeGregori
Engineering Multidimensional Evolutionary Forces to Combat Cancer
Authors: Caroline E. McCoach, Trever G. Bivona
Computational modeling of pancreatic cancer patients receiving FOLFIRINOX and gemcitabine-based therapies identifies optimum intervention strategies
Authors: Kimiyo N. Yamamoto, Akira Nakamura, Lin L. Liu, Shayna Stein, Angela C. Tramontano, ..., Mithat Gonen, Chin Hur, Franziska Michor
#MathOnco Preprints
Prostate-Specific Antigen Dynamics Predict Individual Responses to Intermittent Androgen Deprivation
Authors: Renee Brady, John Nagy, Travis Gerke, Tian Zhang, Andrew Z. Wang, Jingsong Zhang, Robert Gatenby, Heiko Enderling
Rapid evolution and biogeographic spread in a colorectal cancer
Authors: Joao M. Alves, Sonia Prado-Lopez, Jose Manuel Cameselle-Teijeiro, David Posada
Multi-stage models for the failure of complex systems, cascading disasters, and the onset of disease
Authors: Anthony J. Webster
Niche engineering drives early passage through an immune bottleneck in progression to colorectal cancer
Authors: Chandler D. Gatenbee, Ann-Marie Baker, Ryan O. Schenck, Margarida Neves, ..., Simon Leedham, Mark Robertson-Tessi, Trevor A. Graham, Alexander Anderson
Predicting patient-specific radiotherapy responses in head and neck cancer to personalize radiation dose fractionation
Authors: Heiko Enderling, Enakshi Susassee, Jimmy Caudell
#MathOnco - Book of the month
Evolutionary Dynamics: Exploring the Equations of Life
Martin Nowak: This book, "draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves [and] presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner’s Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos."
Most clicked links of April
Can we afford to ignore the role of space in cancer and pre-cancerous tissue any longer?
Prediction of Bone Metastasis in Inflammatory Breast Cancer Using a Markov Chain Model
Stochastic Evolution of Pancreatic Cancer Metastases During Logistic Clonal Expansion
Jobs
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