#MathOnco Issue 67: multi-scale frameworks, adaptive dynamics, plasticity, coexistence theory, ecology on phylogenetic trees
This week in
Math Oncology
May 23, 2019 ~ Issue 67
From the editor
#MathOnco friends,
This week's issue contains manuscripts on multi-scale frameworks, adaptive dynamics, plasticity, and more. I also put a few non-cancer papers on coexistence theory, and ecology on phylogenetic trees which seem relevant. Enjoy!
-Jeffrey West
#MathOnco Publications
Micropharmacology: An In Silico Approach for Assessing Drug Efficacy Within a Tumor Tissue
Authors: Aleksandra Karolak, Katarzyna A. Rejniak
Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer
Authors: Margaret P. Chapman , Tyler Risom, Anil J. Aswani, Ellen M. Langer, Rosalie C. Sears, Claire J. Tomlin
#MathOnco Preprints
A survey of adaptive cell population dynamics models of emergence of drug resistance in cancer, and open questions about evolution and cancer
Authors: Jean Clairambault, Camille Pouchol
An Empiricist's Guide to Modern Coexistence Theory for Competitive Communities
Authors: Casey M. Godwin, Feng-Hsun Chang, Bradley Cardinale
Complex ecological phenotypes on phylogenetic trees: a hidden Markov model for comparative analysis of multivariate count data
Authors: Michael C. Grundler, Daniel L. Rabosky
Heterogeneous multi-scale framework for cancer systems models and clinical applications
Authors: Alokendra Ghosh, Ravi Radhakrishnan
Quantifying Cancer Epithelial-Mesenchymal Plasticity and Its Association with Stemness and Immune Response
Authors: Dongya Jia, Xuefei Li, Federico Bocci, Shubham Tripathi, Youyuan Deng, Mohit Kumar Jolly, José N. Onuchic, Herbert Levine
Dynamic Modeling of Signal Transduction by mTOR Complexes in Cancer
Authors: M. Dorvash, M. Farahmandnia, P. Mosaddeghi, M. Farahmandnejad, H. Saber, M. Khorraminejad-Shirazi, A. Azadi, I. Tavassoly
Researchers Explore a Cancer Paradox
Carl Zimmer: "Healthy cells carry a surprising number of cancer-linked mutations, but they don’t turn into tumors. What’s holding them back?"
#MathOnco - Book of the month
Evolutionary Dynamics: Exploring the Equations of Life
Martin Nowak: This book, "draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves [and] presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner’s Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos."
Most clicked links of April
Can we afford to ignore the role of space in cancer and pre-cancerous tissue any longer?
Prediction of Bone Metastasis in Inflammatory Breast Cancer Using a Markov Chain Model
Stochastic Evolution of Pancreatic Cancer Metastases During Logistic Clonal Expansion
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