#MathOnco Issue 72: first-strike/second-strike; integrated pest management; the evolution of metastases; metabolism in tumors
This week in
Math Oncology
June 27, 2019 ~ Issue 72
From the editor
#MathOnco friends,
Today's issue contains a multitude of evolutionary ideas applied to cancer progression & therapy: first-strike/second-strike, integrated pest management, the evolution of metastases. There are a few articles on metabolism in tumors as well.
Please enjoy,
-Jeffrey West
#MathOnco Publications
Metabolic reprogramming dynamics in tumor spheroids: Insights from a multicellular, multiscale model
Authors: Mahua Roy, Stacey D. Finley
Cancer Treatment Innovators Discover Charles Darwin
Authors: Robert Gatenby, Christopher Whelan
First Strike–Second Strike Strategies in Metastatic Cancer: Lessons from the Evolutionary Dynamics of Extinction
Authors: Robert A. Gatenby, Jingsong Zhang and Joel S. Brown
A call for integrated metastatic management
Authors: Jessica J. Cunningham
Quantitative evidence for early metastatic seeding in colorectal cancer
Authors: Zheng Hu, Jie Ding, Zhicheng Ma, Ruping Sun, ..., Peter Birner, Matthias Preusser, Heinz-Josef Lenz & Christina Curtis
Metabolic Games
Authors: Taneli Pusa, Martin Wannagat and Marie-France Sagot
#MathOnco Preprints
Persistence of cooperation in diffusive public goods games
Authors: Philip Gerlee, Philipp M. Altrock
Antibiotics can be used to contain drug-resistant bacteria by maintaining sufficiently large sensitive populations
Authors: Elsa Hansen, Jason Karslake, Robert J. Woods, Andrew F. Read, Kevin B. Wood
Mathematical oncology: exploiting maths for cancer research
Bio-Physics Research Update: "The journal Physical Biology has now published The 2019 Mathematical Oncology Roadmap, a collection of 11 essays that provide a forward-looking view and demonstrate specific areas of focus within this unique field of research. Introducing the roadmap, Russell Rockne from City of Hope National Medical Center, explains that its dominant theme is the personalization of medicine through mathematics, modelling and simulation – achieved primarily through the use of patient-specific clinical data."
#MathOnco - Book of the month
Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again
Eric Topol: "Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help."
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