#MathOnco Issue 84: cancer eco-evo; mutational distributions; personalized therapy; submit a blog post!
This week in
Math Oncology
Sept. 26, 2019 ~ Issue 84
From the editor
#MathOnco friends,
This week in math oncology includes topics like cancer eco-evo, mutational distributions, and personalized therapy.
I'd like to remind you all that the editors of the Mathematical Oncology Blog are still soliciting posts. If you've recently published a paper, consider writing a brief summary for our "Behind the Paper" series, like the post from Youness Azimzade below. Or submit an original idea or critique to join the discussion over on the blog.
Please enjoy!
-Jeffrey West
#MathOnco Publications
Modeling heterogeneous tumor growth dynamics and cell-cell interactions at single-cell and cell-population resolution
Authors: Leonard A. Harris, Samantha Beik, Patricia M. M. Ozawa, Lizandra Jimenez, Alissa M. Weaver
Time scales and wave formation in non-linear spatial public goods games
Authors: Gregory J. Kimmel, Philip Gerlee, Philipp M. Altrock
Cancer Ecology and Evolution: Positive interactions and system vulnerability
Authors: Frederick R. Adler, Deborah M. Gordon
#MathOnco Preprints
A survey of adaptive cell population dynamics models of emergence of drug resistance in cancer, and open questions about evolution and cancer
Authors: Jean Clairambault, Camille Pouchol
Mutation distribution density in tumors reconstructs human’s lost diversity
Authors: José María Heredia-Genestar, Tomàs Marquès-Bonet, David Juan, Arcadi Navarro
Personalized Cancer Therapy Prioritization Based on Driver Alteration Co-occurrence Patterns
Authors: Lidia Mateo, Miquel Duran-Frigola, Albert Gris-Oliver, Marta Palafox, Maurizio Scaltriti, Pedram Razavi, Sarat Chandarlapaty, Joaquin Arribas, Meritxell Bellet, Violeta Serra, Patrick Aloy
Multi-scale predictions of drug resistance epidemiology suggest a new design principle for rational drug design
Authors: Scott M. Leighow, Chuan Liu, Haider Inam, Boyang Zhao, Justin R. Pritchard
Short-Range Migration Can Alter Evolutionary Dynamics in Solid Tumors
Youness Azimzade: "I have always been fascinated by how movement behavior of species affects their encounters. These encounters should be able to affect the dynamics of populations in larger scale. For tumors, existence of infiltrative edge suggests that we have short range migration and respectively, I wanted to see how those migrations affect evolutionary dynamics in solid tumors. To tackle this problem we developed a discrete border driven model for tumor growth."
#MathOnco - Book of the month
An Editor's Guide to Writing and Publishing Science
Michael Hochberg: "Publishing is rapidly changing, and needs to be explained with a fresh perspective. Simply writing good, clear, concise, science is no longer enough-there is a different mind-set now required that students need to adopt if they are to succeed. The purpose of this book is to provide the foundations of this new approach for both young scientists at the start of their careers, as well as for more experienced scientists to teach the younger generation."
Most clicked links of August
A short comment on statistical versus mathematical modelling
Mathematical Models of Cancer: When to Predict Novel Therapies, and When Not to
Jobs
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Data-driven modeling of breast cancer metastasis - Postdoc (Paul Macklin)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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