#MathOnco Issue 87: evolutionary game dynamics, acid-mediated invasion, radiotherapy, gene surfing, allee effect, sweeps.
This week in
Math Oncology
Oct. 17, 2019 ~ Issue 87
From the editor
Hello!
There were so many excellent preprints/publications released this week! Topics include: evolutionary game dynamics, acid-mediated invasion, radiotherapy, allee effect, and a few interesting genetics models. Be sure also to check out the blog post detailing the exciting math oncology updates out of USC, written by Stacey Finley.
Please enjoy!
-Jeffrey West
#MathOnco Publications
The importance of dead material within a tumour on the dynamics in response to radiotherapy
Authors: Thomas Lewin, Helen Byrne, Philip K Maini, Jimmy J Caudell, Eduardo G Moros, Heiko Enderling
Evolutionary Game Dynamics and Cancer
Authors: Jorge M. Pacheco, Simon A. Levin, David Dingli
An analysis of a mathematical model describing acid‐mediated tumor invasion
Authors: Anderson L. A. de Araujo, Artur C. Fassoni, Luís F. Salvino
#MathOnco Preprints
Unpacking the Allee effect: determining individual-level mechanisms that drive global population dynamics
Authors: Nabil T. Fadai, Stuart T. Johnston, Matthew J. Simpson
Evolution in alternating environments with tunable inter-landscape correlations
Authors: Jeff Maltas, Douglas M. McNally, Kevin B. Wood
From sectors to speckles: The impact of long range migration on gene surfing
Authors: Jayson Paulose, Oskar Hallatschek
Genetic signatures of evolutionary rescue by a selective sweep
Authors: Matthew M. Osmond, Graham Coop
Phenotype-Based Probabilistic Analysis of Heterogeneous Responses to Cancer Drugs and Their Combination Efficacy
Authors: Natacha Comandante-Lou, Mehwish Khaliq, Divya Venkat, Mohan Manikkam, Mohammad Fallahi-Sichani
Mathematical oncology takes root at the University of Southern California
Stacey Finley: "These NIH-funded centers, institutional programs, and individual research labs are inspiration for a new research effort that I am thrilled to lead at the University of Southern California (USC) – the Center for Computational Modeling of Cancer (CCMC). USC’s commitment to interdisciplinary and collaborative research, combined with state-of-the-art resources, make it an optimal setting in which to establish the CCMC. With the Michelson Center for Convergent Bioscience and the Ellison Institute for Transformative Medicine of USC, there is already a rich environment for tackling biomedical research questions. The CCMC will complement and enrich those entities by emphasizing the role of computational modeling and analysis, in the particular context of cancer."
#MathOnco - Book of the month
The Maths of Life and Death
Kit Yates: "In this eye-opening and extraordinary book, Yates explores the true stories of life-changing events in which the application - or misapplication - of mathematics has played a critical role: patients crippled by faulty genes and entrepreneurs bankrupted by faulty algorithms; innocent victims of miscarriages of justice and the unwitting victims of software glitches. We follow stories of investors who have lost fortunes and parents who have lost children, all because of mathematical misunderstandings."
Most clicked links of September
Systems biology approaches to measure and model phenotypic heterogeneity in cancer
Modeling genetic heterogeneity of drug response and resistance in cancer
A Monte Carlo method to estimate cell population heterogeneity
Jobs
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Data-driven modeling of breast cancer metastasis - Postdoc (Paul Macklin)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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