This week in Math Onco: 148
Evolution of cooperation; cancer plasticity; personalized therapy; oncogene addiction
“This week in Mathematical Oncology” — Newsletter
Feb. 4, 2021
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jeffrey.west@moffitt.org
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From the editor:
Summary of contents:
estimates of glioblastoma invasion using
advection–diffusion–reaction equations
a model of
oncogene addiction
, mediated by cell-autonomous and immune-dependent mechanisms
A review: combining biophysical modeling and medical imaging to
design personalized therapy
Glucose-mediated proliferation dynamics of
cancer stem cells
The evolution of cooperation in epithelial cells using
Voronoi tessellation
Model of cancer plasticity describing
specialist and generalist cells
in SCLC
Lastly, an oncologist and a mathematician
walk into a lab
…
Enjoy,
-Jeffrey West
Math, magnets, and medicine: enabling personalized oncology
David A. Hormuth II, Angela M. Jarrett, Guillermo Lorenzo, Ernesto A. B. F. Lima, Chengyue Wu, Caroline Chung, Debra Patt, Thomas E. YankeelovA mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation
Sharon S. Hori, Ling Tong, Srividya Swaminathan, Mariola Liebersbach, Jingjing Wang, Sanjiv S. Gambhir, Dean W. FelsherDormant Tumor Cell Vaccination: A Mathematical Model of Immunological Dormancy in Triple-Negative Breast Cancer
Reza Mehdizadeh, Seyed Peyman Shariatpanahi, Bahram Goliaei, Sanam Peyvandi, Curzio RüeggCancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells
K. J. Pienta, E. U. Hammarlund, J. S. Brown, S. R. Amend, R. M. AxelrodEstimating the extent of glioblastoma invasion
Christian Engwer, Michael Wenske
Cancer Hallmarks Define a Continuum of Plastic Cell States between Small Cell Lung Cancer Archetypes
Sarah Maddox Groves, Abbie Ireland, Qi Liu, Alan J. Simmons, Ken Lau, Wade T. Iams, Darren Tyson, Christine M. Lovly, Trudy G. Oliver, Vito QuarantaCooperative success in epithelial public goods games
Jessie Renton, Karen M. PageUnraveling the origin of Glucose mediated disparate proliferation dynamics of Cancer stem cells
Tagari Samanta, Sandip Kar
1. An oncologist and a mathematician walk into a lab
The Mathematical Oncology Blog
Anum S. Kazerouni and Caleb Phillips: Recent advances in experimental assays and imaging techniques have enabled quantitative measurement of cancer dynamics that can be used to parameterize models of cancer growth and response. Such data-fortified models can be used to guide experimental design and focus the selection of biological measurements to be acquired. These models can also lend insight into cancer mechanisms that may be difficult to measure experimentally.
Apollo's Arrow:
The Profound and Enduring Impact of Coronavirus on the Way We Live
N. Christakis: "Apollo's Arrow offers a riveting account of the impact of the coronavirus pandemic as it swept through American society in 2020, and of how the recovery will unfold in the coming years. Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague — an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species."
NEW: Networks in Cancer: From Symmetry Breaking to Targeted Therapy
Guest Editor: Cristian Axenie, Roman Bauer, María Rodríguez MartínezUnderstanding the Evolutionary Dynamics and Ecology of Cancer in Treatment Resistance
Guest Editor: David BasantaMathematical Models of Cellular Immunotherapies in Cancer
Guest Editors: V. Pérez-García, L. de Pillis, P. Altrock, R. RockneFrom Ecology to Cancer Biology and Back Again
Guest Editors: Fred Adler, Sarah Amend, Chris WhelanFrontiers in quantitative cancer modeling
Guest Editors: Mohit Kumar Jolly, Heiko Enderling
NEW: Research Fellow on modelling the dynamics of the vasculature (Fabian Spill)
NEW: Research Fellow Systems-Mechanobiology of Health and Disease (Fabian Spill)
Early Stage Researcher: Evolutionary therapy in ovarian cancer (Ben Werner)
Postdoc in Statistics & Mathematics for Personalized Breast Cancer Therapy (Alvaro Köhn-Luque)
Mathematical Modeling Expert in Oncology Translational Science (Boehringer Ingelheim)
Research Associate - Biostatistician (University of Manchester)
Postdoctoral Fellow in Cancer Resistance Modeling, Pfizer (Blerta Shtylla)
Principal Scientist – Oncology PK/PD Modelling (Boehringer Ingelheim)
Postdoctoral Research Position in Computational Immunology (Sylvain Cussat-Blanc)
Systems Biology Modeler Positions in Biopharma Consulting Company (Helen Moore)
Computational Approaches to Breast Cancer Evolution - Postdoc (Marc Ryser)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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