This week in Math Onco 165
Public goods, cell signaling, stress-strain, model calibration, clonal hematopoiesis
“This week in Mathematical Oncology” — Newsletter
June 3, 2021
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jeffrey.west@moffitt.org
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From the editor:
Welcome to another edition of “This week in MathOnco,” with exciting topics such as public goods, cell signaling, stress-strain, model calibration, clonal hematopoiesis. I want to draw your attention to two things: 1) a call for Math Onco
poster judges
for
SMB2021
(see the “In the News” section), and 2) this week’s epic cover artwork from the Altrock lab (scroll down!). Please consider submitting your own cover artwork for a future edition.
Enjoy!
-Jeffrey West
Two-dimensional adaptive dynamics of evolutionary public goods games: finite-size effects on fixation probability and branching time
Brian Johnson, Philipp M. Altrock, Gregory J. KimmelCommentary: The publication pandemic
Paul Newton, Katepalli SreenivasanMechanical Models of Pattern and Form in Biological Tissues: The Role of Stress–Strain Constitutive Equations
Chiara Villa, Mark A. J. Chaplain, Alf Gerisch, Tommaso LorenziPatient specific, imaging-informed modeling of rhenium-186 nanoliposome delivery via convection-enhanced delivery in glioblastoma multiforme
Ryan T Woodall, David A Hormuth II, Chengyue Wu, Michael R A Abdelmalik, William T Phillips, Ande Bao, Thomas J R Hughes, Andrew J Brenner, Thomas E YankeelovQuantitative modeling to understand cell signaling in the tumor microenvironment
Min Song, DingLi, Sahak Z. Makaryan, Stacey D. FinleyTreatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations
Gauri A. Patwardhan, Michal Marczyk, Vikram B. Wali, David F. Stern, Lajos Pusztai, Christos HatzisBiomechanical modelling of cancer: Agent-based force-based models of solid tumours within the context of the tumour microenvironment
Cicely K. Macnamara
A protocol for dynamic model calibration
Alejandro F. Villaverde, Dilan Pathirana, Fabian Fröhlich, Jan Hasenauer, Julio R. BangaElucidating Tumor-stromal Metabolic Crosstalk in Colorectal Cancer through Integration of Constraint-Based Models and LC-MS Metabolomics
Junmin Wang, Alireza Delfarah, Patrick Gelbach, Emma Fong, Paul Macklin, Shannon M. Mumenthaler, Nicholas A. Graham, Stacey FinleyGeospatial Cellular Distribution of Cancer-Associated Fibroblasts Significantly Impacts Clinical Outcomes in Metastatic Clear Cell Renal Cell Carcinoma
Nicholas H. Chakiryan, Gregory J. Kimmel, Youngchul Kim, Joseph O. Johnson, …, Liang Wang, James J. Mule, Philipp M. Altrock, Brandon J. ManleyLongitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects
Neil A. Robertson, Eric Latorre-Crespo, Maria Terradas-Terradas, Alison C. Purcell, …, Ian J. Deary, Linus J. Schumacher, Kristina Kirschner, Tamir Chandra
2021 PhysiCell Workshop and Hackathon
Paul Macklin: for fullest consideration, apply by May 31, 2021 at http://PhysiCell.org/ws2021. Follow @PhysiCell (Twitter) and @get.PhysiCell (Instagram) for details.I Read Through 165 Pages of NIH Instructions So You Didn't Have To!
The K99/R00 Getting Started Guide, written by Jenny ChenMath Onco Needs You!
The Math Onco SMB subgroup is looking for volunteers to help judge posters and presentations at the upcoming SMB annual meeting. If you can help out, and are a subgroup member please add your name at the bottom of the following list.
For any questions, please don’t hesitate to reach out to Harsh Jain or Maxi Strobl.
The newsletter now has a dedicated homepage (thisweekmathonco.substack.com), which allows us to post cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. Today’s submission was contributed by Brian Johnson and Gregory Kimmel from the Altrock lab, and is inspired by their recent work on public good games in cancer:
Caption: Our recently published work focuses on population branching behavior in evolutionary game theory. Specifically, we analyze the impact of small population size on the ability of a monomorphic population to diverge into two distinct subgroups. The image shows the qualitative essence of our results alongside potential clinical implications. When mutants arise, their ability to thrive depends on the environment as well as the population size. The effectiveness of treatment is influenced by whether the population has become polymorphic or remains homogeneous.
Networks in Cancer: From Symmetry Breaking to Targeted Therapy
Guest Editor: Cristian Axenie, Roman Bauer, María Rodríguez MartínezUnderstanding the Evolutionary Dynamics and Ecology of Cancer in Treatment Resistance
Guest Editor: David BasantaFrontiers in quantitative cancer modeling
Guest Editors: Mohit Kumar Jolly, Heiko Enderling
Mathematical Immuno-Oncology postdoc (Kasia Rejniak, Moffitt)
Research Fellow in Computational Systems Biology Cancer Research (Simon Mitchell)
PhD student - Measuring cancer evolution in a changing tumour microenvironment (Xiaowei Jiang)
Postdoctoral Scholar - Genetics and Genome Sciences (Christopher McFarland)
Postdoc on colorectal cancer evolution or cancer immunotherapy (Ivana Bozic)
Postdoc on cancer/immune modeling and machine learning (Eduardo Sontag)
Early Stage Researcher: Evolutionary therapy in ovarian cancer (Ben Werner)
Research Associate - Biostatistician (University of Manchester)
Systems Biology Modeler Positions in Biopharma Consulting Company (Helen Moore)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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