This week in MathOnco 159
Parameter estimation, GRNs, chalkboard art, CRC microenvironment, and more
“This week in Mathematical Oncology” — Newsletter
Apr. 22, 2021
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jeffrey.west@moffitt.org
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From the editor:
Summary of contents:
Perivascular-niche
dynamics
The
art
of writing on chalkboards
A new open
dataset
on impact of microenvironment on CRC growth - useful for model building.
GRN’s
combined
with external cell-cell signaling (stochastic-deterministic modeling)
A new
postdoc
opportunity at Moffitt (Kasia Rejniak)
Enjoy,
-Jeffrey West
Standing Variations Modeling Captures Inter-Individual Heterogeneity in a Deterministic Model of Prostate Cancer Response to Combination Therapy
Harsh Vardhan Jain, Inmaculada C. Sorribes, Samuel K. Handelman, Johnna Barnaby, Trachette L. JacksonComputational modelling of perivascular-niche dynamics for the optimization of treatment schedules for glioblastoma
Amanda Randles, Hans-Georg Wirsching, Jamie A. Dean, Yu-Kang Cheng, Samuel Emerson, Siobhan S. Pattwell, Eric C. Holland, Franziska MichorHigh-throughput microscopy reveals the impact of multifactorial environmental perturbations on colorectal cancer cell growth
Chun-Te Chiang, Roy Lau, Ahmadreza Ghaffarizadeh, Matthew Brovold, Dipen Vyas, Edwin F Juárez, Anthony Atala, David B Agus, Shay Soker, Paul Macklin, Daniel Ruderman, Shannon M Mumenthaler
A single-cell resolved cell-cell communication model explains lineage commitment in hematopoiesis
Megan K. Franke, Adam L. MacLeanSpatial genomics maps the structure, character and evolution of cancer clones
Artem Lomakin, Jessica Svedlund, Carina Strell, Milana Gataric, …, Peter J Campbell, Moritz Gerstung, Mats Nilsson, Lucy R YatesCollateral Responses to Classical Cytotoxic Chemotherapies are Heterogeneous and Sensitivities are Sparse
Simona Dalin, Douglas A. Lauffenburger, Michael T. HemannTargeting Adaptation to Cancer Treatment by Drug Combinations
Heping Wang, Augustin Luna, Gonghong Yan, Xubin Li, Ozgun Babur, Gordon B. Mills, Chris Sander, Anil KorkutA Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
João P.G. Santos, Kadri Pajo, Daniel Trpevski, Andrey Stepaniuk, Olivia Eriksson, Anu G. Nair, Daniel Keller, Jeanette Hellgren Kotaleski, Andrei Kramer
1. The Art of Mathematics in Chalk
Scientific American
Clara Moskowitz: “As Wynne began to travel to different universities to meet more mathematicians, she discovered how diverse their chalkboard styles are. “Some were very clean and neat and very carefully considered,” she recalls. “And some were just this explosion and chaos. The chalkboards almost felt like portraits of the person and depended on the personality of the mathematician.””
Atomic Habits:
An Easy & Proven Way to Build Good Habits & Break Bad Ones
James Clear: "If you're having trouble changing your habits, the problem isn't you. The problem is your system. Bad habits repeat themselves again and again not because you don't want to change, but because you have the wrong system for change. You do not rise to the level of your goals. You fall to the level of your systems. Here, you'll get a proven system that can take you to new heights."
Networks in Cancer: From Symmetry Breaking to Targeted Therapy
Guest Editor: Cristian Axenie, Roman Bauer, María Rodríguez MartínezUnderstanding the Evolutionary Dynamics and Ecology of Cancer in Treatment Resistance
Guest Editor: David BasantaFrom Ecology to Cancer Biology and Back Again
Guest Editors: Fred Adler, Sarah Amend, Chris WhelanFrontiers in quantitative cancer modeling
Guest Editors: Mohit Kumar Jolly, Heiko Enderling
NEW: Mathematical Immuno-Oncology postdoc (Kasia Rejniak, Moffitt)
Research Fellow in Computational Systems Biology Cancer Research (Simon Mitchell)
PhD student - Measuring cancer evolution in a changing tumour microenvironment (Xiaowei Jiang)
Postdoctoral Scholar - Genetics and Genome Sciences (Christopher McFarland)
Postdoc on colorectal cancer evolution or cancer immunotherapy (Ivana Bozic)
Postdoc on cancer/immune modeling and machine learning (Eduardo Sontag)
Early Stage Researcher: Evolutionary therapy in ovarian cancer (Ben Werner)
Mathematical Modeling Expert in Oncology Translational Science (Boehringer Ingelheim)
Research Associate - Biostatistician (University of Manchester)
Postdoctoral Fellow in Cancer Resistance Modeling, Pfizer (Blerta Shtylla)
Principal Scientist – Oncology PK/PD Modelling (Boehringer Ingelheim)
Postdoctoral Research Position in Computational Immunology (Sylvain Cussat-Blanc)
Systems Biology Modeler Positions in Biopharma Consulting Company (Helen Moore)
Computational Approaches to Breast Cancer Evolution - Postdoc (Marc Ryser)
Math/statistical models of stem cell lineage dynamics and cancer genomics - Postdoc (Adam MacLean)
Postdoctoral Research Position in Computational Oncology (Tom Yankeelov)
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