This week in MathOnco 171
1000 subs (& MathOnco merch)!
“This week in Mathematical Oncology” — Newsletter
July 22, 2021
From the editor:
This week marks a huge milestone: 1000 subscribers to the newsletter. Thanks for subscribing! To celebrate, a few of us (thanks Jill Gallaher, Maximilian Strobl, Chandler Gatenbee, and Sandy Anderson) brainstormed some MathOnco themed art. Click
to see find a t-shirt or a coffee mug to celebrate MathOnco science! In addition, I’ve written a post describing the journey and some of the back story of
the past 185 weeks
As always, scroll down for this week’s release of papers, preprints, a blog post. Enjoy!
- Jeffrey West
The Evolutionary Ecology of Dormancy in Nature and in Cancer
Anna K. Miller, Joel S. Brown, Heiko Enderling, David Basanta, Christopher J. Whelan
Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment
Catherine Gutierrez, Aziz M. Al’Khafaji, Eric Brenner, Kaitlyn E. Johnson, …, Anthony Letai, Gad Getz, Catherine J. Wu, Amy Brock
Interdisciplinary research: shaping the healthcare of the future
Stephen Smye, Alejandro Frangi
Coupled Source-Sink Habitats Produce Spatial and Temporal Variation of Cancer Cell Molecular Properties as an Alternative to Branched Clonal Evolution and Stem Cell Paradigms
Jessica J. Cunningham, Anuraag Bukkuri, Joel S. Brown, Robert J. Gillies, Robert A. Gatenby
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data
Timon Heide, Jacob Househam, George D Cresswell, Inmaculada Spiteri, …, Manuel Rodriguez-Justo, Luca Magnani, Trevor A Graham, Andrea Sottoriva
The Fundamental Theorem of Natural Selection
John C. Baez
The past 185 weeks in MathOnco
The Mathematical Oncology Blog
Jeffrey West: “After reaching 1,000 subscribers to “This week in MathOnco,” it’s a good time to reflect on how we got here. When I first floated the idea of a newsletter to my postdoc supervisor (Sandy Anderson) our main concern was the sustainability of the idea. How many relevant articles are published each week? Not to mention, would anyone find the curated list useful or helpful?”
Why we should use coordination games in cancer
The Mathematical Oncology Blog
Péter Bayer: “At the end of the talk Joel expressed what is arguably the main point of the project. Cancer is an evolutionary system. As an ecologist, he spent most of his career trying to understand such systems to figure out ways by which humanity is able to sustain a rich, diverse, and beautiful ecosystem. ‘Now that I’m older’ he said ‘I would like to find a way to break the ecosystem. Specifically, I want to use evolutionary game theory to destroy the cancer ecosystem’.”
The newsletter now has a dedicated homepage (thisweekmathonco.substack.com), which allows us to post cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. Today’s submission was contributed by Jill Gallaher, Maximilian Strobl, Jeffrey West, and Sandy Anderson.
Caption: The letters of the text “This week in MathOnco” provide a chemotactic signal for migrating cells (in white). Cells within basins of high concentration are allowed to proliferate and expand to fill the domain. After some time, the chemotactic signal changes to display “1000” to celebrate 1000 subscribers to the newsletter. Built in HAL, using off-lattice, agent-based grids in combination with PDE grids.
Created by: Jill Gallaher, Maximilian Strobl, Jeffrey West, and Sandy Anderson
Non-Local Cell Adhesion Models
Symmetries and Bifurcations in 1-D
Authors: Buttenschoen, Andreas, Hillen, Thomas: “While deeply grounded in the biological application of cell adhesion and tissue formation, this monograph focuses on the mathematical analysis of non-local adhesion models. The novel aspect is the non-local term (an integral operator), which accounts for forces generated by long ranged cell interactions. The analysis of non-local models has started only recently, and it has become a vibrant area of applied mathematics.”
Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.
Current subscriber count: 1k