This week in MathOnco 196
Combination therapy drug action, evolutionary therapy in metastatic Ewing sarcoma, selection forces in aging, model pre-registration, lineage tracing, and more
“This week in Mathematical Oncology” — Feb. 10, 2022
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mathematical-oncology.org
From the editor:
Today’s issue is packed full of exciting articles on combination therapy drug action, evolutionary therapy in metastatic Ewing sarcoma, selection forces in aging, model pre-registration, lineage tracing, model uncertainty and more.
Jeffrey West
jeffrey.west@moffitt.org
Intermittent Hormone Therapy Models Analysis and Bayesian Model Comparison for Prostate Cancer
S. Pasetto, H. Enderling, R. A. Gatenby & R. Brady-NichollsIndependent Drug Action in Combination Therapy: Implications for Precision Oncology
Deborah Plana, Adam C. Palmer and Peter K. SorgerA Proposed Trial Design for the Treatment of Widely Metastatic Ewing Sarcoma Inspired by Evolutionary Dynamics
Jonathan Metts, Thomas Russell, Damon Reed, Matteo TruccoThe selection force weakens with age because ageing evolves and not vice versa
Stefano Giaimo, Arne TraulsenPre-registration of mathematical models
John P.A. IoannidisSurvival in branching cellular populations
Adam S. Bryant, Maxim O. LavrentovichOptimal regulation of tumour-associated neutrophils in cancer progression
Aurelio A. de los Reyes, Yangjin KimFunctionalized Lineage Tracing for the Study and Manipulation of Heterogeneous Cell Populations
Andrea Gardner, Daylin Morgan, Aziz Al’Khafaji, Amy Brock
Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer
Meredith S Brown, Behnaz Abdollahi, Owen M Wilkins, Hanxu Lu, …, Mohit Kumar Jolly, Brock Christensen, Saeed Hassanpour, Diwakar R PattabiramanThe extinction time under mutational meltdown
Lucy Lansch-Justen, Davide Cusseddu, Mark A. Schmitz, Claudia BankThe transformability of genotype-phenotype landscapes
Malvika Srivastava, Joshua L. PayneModelling the effect of vascular status on tumour evolution and outcome after thermal therapy
Jesús J. Bosque, Gabriel F. Calvo, María Cruz NavarroApproximate Bayesian Computation Based on Maxima Weighted Isolation Kernel Mapping
Iurii S. Nagornov
The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group.
Caption: Integrated Mathematical Oncology, where my mathematics met the biology of my body. In the picture, the prostate (in red) and the skeleton around the pelvis area are shown. A study of the intermittent hormone therapy models for prostate cancer in a Bayesian framework is the topic of my most recent paper. Have a look!
Created by: Stefano Pasetto (@StefanoPasetto), Maxi Strobl (@StroblMAR) & Sandy Anderson (@ara_anderson)
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