This week in MathOnco 207
Radiotherapy tumor-immune interactions, patient-specific optimization, tumor hypoxia, minimum effective dose, adaptive predictive control, and more
“This week in Mathematical Oncology” — Apr. 28, 2022
> mathematical-oncology.org
From the editor:
Welcome to a new week of Math Oncology, which features papers on radiotherapy tumor-immune interactions, patient-specific optimization, tumor hypoxia, minimum effective dose, adaptive predictive control, and more! Enjoy ~
Jeffrey West
jeffrey.west@moffitt.org
Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system
Rebecca Anne Bekker, Sungjune Kim, Shari Pilon-Thomas, Heiko EnderlingA Continuum Mathematical Model of Substrate-Mediated Tissue Growth
Maud El-Hachem, Scott W. McCue, Matthew J. SimpsonEarly response dynamics predict treatment failure in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with cetuximab and nivolumab
Daniel J. Glazar, Matthew Johnson, Joaquim Farinhas, Conor E. Steuer, Nabil F. Saba, Marcelo Bonomi, Christine H. Chung, Heiko EnderlingEfficient simulation of clinical target response surfaces
Daniel Lill, Anne Kümmel, Venelin Mitov, Daniel Kaschek, Nathalie Gobeau, Henning Schmidt, Jens TimmerTowards patient-specific optimization of neoadjuvant treatment protocols for breast cancer based on image-guided fluid dynamics
Chengyue Wu, David Hormuth, Guillermo Lorenzo, Angela Jarrett, Federico Pineda, Frederick M. Howard, Greg Karczmar, Thomas E. YankeelovQuantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
Torgeir Mo, Siri Helene Bertelsen Brandal, Alvaro Köhn-Luque, Olav Engebraaten, Vessela N. Kristensen, Thomas Fleischer, Tord Hompland, Therese Seierstad
Containing Cancer with Personalized Minimum Effective Dose
Masud M A, Jae-Young Kim, Eunjung KimABC of the Future
Henri Pesonen, Umberto Simola, Alvaro Köhn-Luque, Henri Vuollekoski, …, David T. Frazier, Worapree Maneesoonthorn, Gael M. Martin, Jukka CoranderExternal control of cancer cellular dynamics using adaptive model predictive control
Benjamin Smart, Irene de Cesare, Ludovic Renson, Lucia MarucciQuantitative landscapes reveal trajectories of cell-state transitions associated with drug resistance in melanoma
Maalavika Pillai, Zihao Chen, Mohit Kumar Jolly, Chunhe LiBayesian Parameter Estimation for Dynamical Models in Systems Biology
Nathaniel J Linden, Boris Kramer, Padmini RangamaniMicrobial mutualism generates multistable and oscillatory growth dynamics
Daniel B. Amchin, Alejandro Martínez-Calvo, Sujit S. Datta
New Proof Illuminates the Hidden Structure of Common Equations
Quanta Magazine
"Van der Waerden’s conjecture mystified mathematicians for 85 years. Its solution shows how polynomial roots relate to one another.”
The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group.
Caption: The artwork represents some results of our recent study investigating the consequence of spatial distribution of fibroblast and resistant cells on the therapy outcomes. Our analysis shows that the time to progression is correlated with the area of fibroblast impact. Towards left (from the middle) it shows the cell population count under maximum tolerated continuous therapy. Towards right (from the middle) it shows the same under adaptive therapy. The first row shows tumor growth without fibroblast, while the other three rows show tumor growth with different fibroblast structures which accelerate the progression under both type of treatment strategy. The fourth row shows the quickest progression as it is for the case with largest area of impact.
Created by: Masud M A & Eunjung Kim
Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.
1. Jobs
PhD fellow position in mathematical health and disease modeling, Roskilde University (Morten Andersen) - Deadline: 5/7/2022
Postdoctoral positions in mathematical oncology (Kasia Rejniak, Moffitt) - Open until filled
Current subscriber count: >1.1k