This week in MathOnco 219
3D epithelia, combination chemo, androgen deprivation & immunotherapy, spatial modeling in Julia, turnover
“This week in Mathematical Oncology” — July 21, 2022
From the editor:
Today we feature articles on 3D epithelia, combination chemo, androgen deprivation & immunotherapy, spatial modeling in Julia, turnover, and more. Enjoy,
"Somewhere, something incredible is waiting to be known."
- S. Begley
Self-organization in brain tumors: How cell morphology and cell density influence glioma pattern formation
Sara Jamous, Andrea Comba, Pedro R. Lowenstein, Sebastien Motsch
A quantitative biophysical principle to explain the 3D cellular connectivity in curved epithelia
Pedro Gómez-Gálvez, Pablo Vicente-Munuera, Samira Anbari, Antonio Tagua, …, Rafael Robles, Alberto Márquez, Javier Buceta, Luis M. Escudero
Drug independence and the curability of cancer by combination chemotherapy
Amy E. Pomeroy, Emmett V. Schmidt, Peter K. Sorger, Adam C. Palmer
Combining Androgen Deprivation and Immunotherapy in Prostate Cancer Treatment: A Mechanistic Approach
Johnna Barnaby, Harsh Vardhan Jain
Integrating digital pathology and mathematical modelling to predict spatial biomarker dynamics in cancer immunotherapy
L. G. Hutchinson, O. Grimm
A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells
Mariangela Russo, Simone Pompei, Alberto Sogari, Mattia Corigliano, …, Federica Di Nicolantonio, Alberto Bardelli, Marco Cosentino Lagomarsino
Statistical considerations for analyses of time-to-event endpoints in oncology clinical trials: Illustrations with CAR-T immunotherapy studies
Yimei Li, Wei-Ting Hwang, Shannon L. Maude, David T. Teachey, …, Hongyan Liu, David L. Porter, Stephan A. Grupp, Pamela A. Shaw
J-SPACE: a Julia package for the simulation of spatial models of cancer evolution and of sequencing experiments
Fabrizio Angaroni, Alessandro Guidi, Gianluca Ascolani, Alberto d’Onofrio, Marco Antoniotti, Alex Graudenzi
Scale-free correlations and criticality in explants derived from an orthotopic model of brain cancer
Kevin B. Wood, Andrea Comba, Sebastien Motsch, Tomás S. Grigera, Pedro Lowenstein
Pattern formation and front stability for a moving-boundary model of biological invasion and recession
Alexander K. Y. Tam, Matthew J. Simpson
SHAPR predicts 3D cell shapes from 2D microscopic images
Dominik J. E. Waibel, Niklas Kiermeyer, Scott Atwell, Ario Sadafi, Matthias Meier, Carsten Marr
Turnover shapes evolution of birth and death rates
Teemu Kuosmanen, Simo Särkkä, Ville Mustonen
Tumor subclones, where are you?
Xianbin Su, Shihao Bai, Gangcai Xie, Yi Shi, Linan Zhao, Guoliang Yang, Futong Tian, Kun-Yan He, Lan Wang, Xiaolin Li, Qi Long, Ze-Guang Han
Automatic detection of spatio-temporal signalling patterns in cell collectives
Paolo Armando Gagliardi, Benjamin Grädel, Marc-Antoine Jacques, Lucien Hinderling, …, Gerald Kastberger, Olivier Pertz, Maciej Dobrzyński
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