This week in MathOnco 268

IMO Workshop 11 and more

“This week in Mathematical Oncology” — September 14, 2023

> mathematical-oncology.org

From the editor:

This week’s issue is themed around the IMO Workshop — come join us at Moffitt from Oct 29 - Nov 2. Apply by 9/30 for travel scholarships!

Thanks,

Jeffrey West
jeffrey.west@moffitt.org

1. Mutation rates and fitness consequences of mosaic chromosomal alterations in blood
   Caroline J. Watson & Jamie R. Blundell

2. How do microbes grow in nature? The role of population dynamics in microbial ecology and evolution
   Justus Wilhelm Fink, Michael Manhart

3. Addressing challenges in evolutionary medicine: three priorities
   Michael E. Hochberg

1. Critical Evaluation of Artificial Intelligence as Digital Twin of Pathologist for Prostate Cancer Pathology
   Okyaz Eminaga, Mahmoud Abbas, Christian Kunder, Yuri Tolkach, …, Robert West, Jin Long, Richard Fan, Olaf Bettendorf

2. Mutually exclusive teams-like patterns of gene regulation characterize phenotypic heterogeneity along the noradrenergic-mesenchymal axis in neuroblastoma
   Manas Sehgal, Sonali Priyadarshini Nayak, Sarthak Sahoo, Jason A Somarelli, Mohit Kumar Jolly

3. Parameter identifiability and model selection for partial differential equation models of cell invasion
   Yue Liu, Kevin Suh, Philip K. Maini, Daniel J. Cohen, Ruth E. Baker

4. A calibration and uncertainty quantification analysis of classical, fractional and multiscale logistic models of tumour growth
   Nikolaos M. Dimitriou, Ece Demirag, Katerina Strati, Georgios D. Mitsis

5. Agent-based modeling of tumor-immune interactions reveals determinants of final tumor states
   Manal Ahmidouch, Neel Tangella, Stacey D Finley

6. Low dimensionality of phenotypic space as an emergent property of coordinated teams in biological regulatory networks
   Kishore Hari, Pradyumna Harlapur, Aashna Saxena, Kushal Haldar, Aishwarya Girish, Tanisha Malpani, Herbert Levine, View ORCID ProfileMohit Kumar Jolly

1. Games and the Treatment Convexity of Cancer
   The Mathematical Oncology Blog
   Jeffrey West: “Recently, I had the opportunity to collaborate with Péter Bayer on a paper that eventually found its way into a special issue on Evolutionary Games and Applications. The paper represents a fun merging of two fields: 1) evolutionary game theory and 2) treatment convexity. Rather than write a simple summary of the paper, I thought it would be more exciting to write some of the history of the project as well as a forward-thinking view of what's next.“

2. How Darwinism is changing medicine
   BBC Future
   Sofia Quaglia: “The relatively new discipline of evolutionary medicine is making strides in the fields of cancer treatment and antibacterial resistance.“

The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. This week’s artwork:

Artist: Sandy Anderson (@ara_anderson), Jill Gallaher (@jillagal) and Chandler Gatenbee (@cgatenbee)

Caption: Registration page for the 11th Integrated Mathematical Oncology workshop at the Moffitt Cancer Center is now open: imo11.eventbrite.com. The IMO workshop is designed to motivate and facilitate a hands-on modeling experience focused on Steering cancer evolution through therapeutic intervention. We are offering deluxe travel awards for external participation - so apply asap!

Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.

1. Jobs

• Postdoctoral Research Scientist in Deconstructing organisational principles of tumour microenvironments through spatial data analysis and computational modelling (Dr Xiao Fu; CRUK Beatson Institute, Glasgow Scotland)

• Staff Scientist - Translational Bioinformatics (City of Hope)

2. Conferences / Meetings

• Computational models of life: From molecular biology to digital twins

3. Special issues

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