This week in MathOnco 274

Identifiability analysis, clonal expansion, spatial biology, stochastic dynamics, and more.

“This week in Mathematical Oncology” — Nov. 2, 2023

> mathematical-oncology.org

From the editor:

Today’s newsletter contains articles on identifiability analysis, clonal expansion, spatial biology, stochastic dynamics, and more.

Enjoy,

Jeffrey West
jeffrey.west@moffitt.org

Is there something we missed?

Submit your recent paper or preprint here:
https://mathematical-oncology.org/newsletter

1. Optimizing IFN Alpha Therapy against Myeloproliferative Neoplasms
   Gurvan Hermange, Paul-Henry Cournède and Isabelle Plo

2. Stochastic model for cell population dynamics quantifies homeostasis in colonic crypts and its disruption in early tumorigenesis
   Konstantinos Mamis, Ruibo Zhang and Ivana Bozic

3. Stochastic tumor-immune interaction model with external treatments and time delays: An optimal control problem
   H. J. Alsakaji, F. A. Rihan, K. Udhayakumar, F. El Ktaibi

4. Network Inference from Cancer and Epithelial Cell Co-Culture Reveal Microenvironmental Configurations That Drives Population Dynamics
   Alexandre Sarmento Queiroga, Mauro Cesar Cafundó Morais, Beatriz Stransky

5. Spatial biology of Ising-like synthetic genetic networks
   Kevin Simpson, Alfredo L’Homme, Juan Keymer & Fernán Federici

6. Physics-based tissue simulator to model multicellular systems: A study of liver regeneration and hepatocellular carcinoma recurrence
   Luciana Melina Luque ,Carlos Manuel Carlevaro ,Camilo Julio Llamoza Torres,Enrique Lomba

1. Minimally Sufficient Experimental Design using Identifiability Analysis
   Irina Kareva, Jana Gevertz

2. Pan-cancer evolution signatures link clonal expansion to dynamic changes in the tumour immune microenvironment

   Xinyu Yang, Wei Liu, Geoff Macintyre, Peter Van Loo, Florian Markowetz, Peter Bailey, Ke Yuan

3. Interfacial morphodynamics of proliferating microbial communities
   Alejandro Martinez-Calvo, Carolina Trenado-Yuste, Hyunseok Lee, Jeff Gore, Ned S Wingreen, Sujit S Datta

1. NIH revises grant review process to improve focus on scientific merit, reduce reputational bias

The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. This week’s artwork:

Integrated Mathematical Oncology PhD
Deadline: December 1, 2023

We’d like to invite you to apply to Moffitt Cancer Center’s PhD program in the Integrated Mathematical Oncology track, which consists of focused training in mathematical modeling for cancer biology and clinical oncology problems.

Students will receive interdisciplinary training in the broader field of cancer biology and immunology through coursework and immersion in the Moffitt Cancer Center’s research endeavors, in collaboration with the University of South Florida.

Moffitt Cancer Center has the largest group of mathematical oncologists in its unique Integrated Mathematical Oncology department. Moffitt Cancer Center is the central hub for translational mathematical modeling research, providing a unique training environment for graduate studies.

We're on the lookout for students who are not only good with mathematical models but can also dive deep into discussions about biology with biologists and chat about clinical data with doctors.

The program offers full tuition, health insurance, and a stipend. Apply before December 1st at this link:

Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.

1. Jobs

• Postdoc Positions in Computational Modeling of Cancer Therapeutics and Developing Methods for Analyzing Multiscale Agent-Based Models at the University of Michigan (Trachette Jackson)

• TMDC Scientific Director (University of Minnesota-Twin Cities: College of Science and Engineering)

• Postdoctoral Associate (University of Minnesota, School of Mathematics; Dave Odde, Kevin Leder, Jasmine Foo) in Mechanistic mathematical modeling and engineering in therapeutic design

2. Conferences / Meetings

3. Special issues

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