This week in MathOnco 316

Year in recap, stochastic models, spatial models, and cooperation in cancer...

“This week in Mathematical Oncology” — Jan 9, 2024

> mathematical-oncology.org

From the editor:

Happy New Year! Already nostalgic about 2024? Check out the year in recap post by David Basanta (the Mathematical Oncology Blog’s Editor).

Please bear with me, as these next few issues will be packed with all the literature & news published over the break.

For example, we’ve added a note on elections for the ISEEC society, with a deadline for nominations until Monday 19th January.

There are quite a few job posts below, too ~

Enjoy,

Jeffrey West
jeffrey.west@moffitt.org

1. A multiscale model of immune surveillance in micrometastases gives insights on cancer patient digital twins
   Heber L. Rocha, Boris Aguilar, Michael Getz, Ilya Shmulevich, Paul Macklin

2. An expanded view of cell competition
   Ameya Khandekar, Stephanie J. Ellis

3. Spatial organization of mediated-macrophage chemoprotective niches in solid tumors: A mathematical analysis

   William Dangelser, Angelique Stephanou, Arnaud Millet

4. Stochastic models allow improved inference of microbiome interactions from time series data
   Román Zapién-Campos, Florence Bansept, Arne Traulsen

5. Competition for resources can reshape the evolutionary properties of spatial structure
   Anush Devadhasan, Oren Kolodny, Oana Carja

6. Sociobiology meets oncology: unraveling altruistic cooperation in cancer cells and its implications
   Muhammad Sufyan bin Masroni, Evelyn Siew-Chuan Koay, Victor Kwan Min Lee, Siok Bian Ng, Soo Yong Tan, Karen Meiling Tan, Marco Archetti & Sai Mun Leong

7. Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life
   Jesse Kreger, Jazlyn A. Mooney, Darryl Shibata & Adam L. MacLean

8. A mathematical framework for comparison of intermittent versus continuous adaptive chemotherapy dosing in cancer
   Cordelia McGehee, Yoichiro Mori

1. Linking spatial drug heterogeneity to microbial growth dynamics in theory and experiment
   Zhijian Hu, Yuzhen Wu, Tomas Freire, Erida Gjini, Kevin Wood

2. MuSpAn: A Toolbox for Multiscale Spatial Analysis
   Joshua Bull, Joshua Moore, Eoghan Mulholland, Simon Leedham, Helen Byrne

3. CNSistent integration and feature extraction from somatic copy number profiles
   Adam Streck, Roland F. Schwarz

1. Please can you add the following announcement to this week's newsletter?

   The International Society for Evolution, Ecology, and Cancer is seeking nominations and self-nominations for its leadership roles.

   Please submit your nominations via this online form by 19th January. The form includes a link to further information about each post.

   Elections will be conducted later in January and new officers will begin their terms in February.
   

   The mission of the International Society for Evolution, Ecology and Cancer is to advance cancer research and clinical management by employing evolutionary, comparative and ecological approaches and principles to cancer biology, prevention, and treatment. By bringing together cancer biologists, evolutionary biologists, ecologists, quantitative modelers, bioinformaticians and clinicians, the society seeks to enable collaboration at the interface of these fields, the exchange of research findings, novel methodologies and theoretical frameworks across disciplines.
   

   ISEEC supports education and outreach efforts to train the next generation of scientists in the evolution and ecology of cancer, as well as engaging the public in fundamental questions about the nature and evolutionary origins of cancer.

   Past ISEEC Presidents include Michael Hochberg, Carlo Maley and James DeGregori. The incoming President is Athena Aktipis.

2. Heiko Enderling

   Math Oncology Interviews by Thomas Hillen (YouTube)

The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. This week’s artwork:

Based on the blog post: A Year in Mathematical Oncology: 2024 Blog Recap

Artist: David Basanta

Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.

1. Jobs

• Assistant Professorships in Applied Mathematics, Data Science, and Optimisation, University of Birmingham

• Assistant Professorships in Mathematics, with a focus on consolidating connections between the Schools of Mathematics and Computer Science, University of Birmingham

• 125 Anniversary Fellows and Chairs (Faculty positions at any rank), University of Birmingham

• Research Fellow for Modelling of Ageing and Diseases, University of Birmingham ("Systems-Mechanobiology of Health and Disease," led by Professor Fabian Spill)

• PhD Student Modelling Metabolic Drivers of Ageing and Diseases (Fabian Spill, University of Birmingham) - Open until filled

• Postdoc in Conquering Therapy Resistance in Multiple Myeloma using Advanced Computational Tools (Dr. Jeroen Guikema, Dr. Katerina Stankova and Prof. Antoine van Kampen)

2. Conferences / Meetings

3. Special issues

• Spatial tumor heterogeneity (BMC Cancer; Xiao Fu, Weini Huang, Robert Noble, Dmitrii Shek) - Submission deadline: 12th Sep 2025

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