This week in MathOnco 331
Wiki page, adaptive therapy, model calibration, tumor ecology, and modeling toxicity.
“This week in Mathematical Oncology” — May 15, 2025
> mathematical-oncology.org
From the editor:
This week’s edition of the Math Onco newsletter contains articles on important subjects like adaptive therapy, model calibration, tumor ecology, and modeling toxicity.
Also, for those interested in Wikipedia, Russ Rockne’s group started an initiative to create a page for Mathematical Oncology. Can you take a look, and add a few relevant details and links that might be useful to the general public?
Enjoy,
Jeffrey West
jeffrey.west@moffitt.org
Optimal adaptive cancer therapy based on evolutionary game theory
Zhiqing Li, Xuewen Tan , Yangtao YuFast model calibration for predicting the response of breast cancer to chemotherapy using proper orthogonal decomposition.
Christenson C, Wu C, Hormuth DA 2nd, Stowers CE, LaMonica M, Ma J, Rauch GM, Yankeelov TEVirtual cells for predictive immunotherapy
Daniel R. Bergman & Elana J. FertigBlocking cancer-fibroblast mutualism inhibits proliferation of endocrine therapy resistant breast cancer
Jason I Griffiths, Feng Chi, Elena Farmaki, Eric F Medina, …, Qamar J Khan, Aritro Nath, Jeffrey T Chang, and Andrea H Bild
Tumor Landscape Analysis: An Ecologically Informed Framework to Understand Tumor Microenvironments
Luis Cisneros, Merih Deniz Toruner, Martin E. Fernandez-Zapico, Carlo C. Maley, Ryan M CarrMapping Tumor Microenvironment and Treatment Response of Diffuse Midline Glioma Using Multiplexed Immunofluorescence and AI Models
Sandra Laternser, Andrea Joseph De Micheli, Sarah Brüningk, …, Roger Packer, Miriam Bornhorst, Marta María Alonso, Javad NazarianDelaying Cancer Progression by Integrating Toxicity Constraints in a Model of Adaptive Therapy
Jana L. Gevertz, Harsh Vardhan Jain, Irina Kareva, Kathleen P Wilkie, Joel Brown, Yitong Pepper Huang, Eduardo Sontag, Vladimir Vinogradov, Mark DaviesSpatiotemporal Simulation of Radiotherapy Impact on Stage III Sigmoid Colon Cancer Using a Metabolically Coupled Agent-Based Model
Sa Dhrmasastha Karthikeya, Prathiba JonnalaTumorTwin: A python framework for patient-specific digital twins in oncology
Michael Kapteyn, Anirban Chaudhuri, Ernesto A.B.F. Lima, Graham Pash, Rafael Bravo, Karen Willcox, Thomas E. Yankeelov, David A. Hormuth IILymphocytes and monocytes undergo swift suppression of IL-10R, IL-6R, and IL-2Rβγ signaling under high concentrations of different cytokines
Maxim Kuznetsov, Joao Rodrigues Lima Junior, Russell C Rockne, Sergio Branciamore, Andrei S Rodin, Peter P LeeFluctuating growth rates link turnover and unevenness in species-rich communities
Emil Mallmin, Arne Traulsen, Silvia De Monte
Math Oncology Interviews by Thomas Hillen (YouTube)
2. Novel color via stimulation of individual photoreceptors at population scale
James Fong, Hannah K. Doyle, Congli Wang, Alexandra E. Boehm, Sofie R. Herbeck, …, William S. Tuten, Ramkumar Sabesan, Austin Roorda, Ren Ng
The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. This week’s artwork:
Based on: The Annual Meeting of the American Association for Cancer Research 2025
Artist: Maximilian Strobl (with image credits to the Mathonco community)
Caption: This week’s cover showcases some of the exciting Mathonco representation at the AACR Annual Meeting 2025, which was held in Chicago two weeks ago. From the evolutionary game theory of VEGF, to mathematical models of circulating tumor DNA, or virtual gleason scores a wealth of fantastic new science was presented. This was rounded off by great Mathonco-infused sessions on tumor heterogeneity, the role of AI in cancer, and adaptive therapy, and several fun evenings. Also, check out the Mathonco articles that were highlighted by AACR as part of their cross-journal collection series, such as the brand-new review by Ranjini Bhattacharya on an evolutionary take on cancer’s hallmarks, or Kit Gallagher’s paper on DRL-informed adaptive therapy. If you’d like to highlight impressions and experiences from a recent conference, feel free to reach out to me.
Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.
1. Jobs
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