This week in MathOnco 218
Immunotherapy, “oncostreams”, Fisher-Kolmogorov models, evolutionary scales, and more
“This week in Mathematical Oncology” — July 14, 2022
From the editor:
Today we feature articles on immunotherapy, “oncostreams”, Fisher-Kolmogorov models, evolutionary scales, and more. Enjoy,
"The outcome of the peer review process is a random variable whose mean is determined by the quality of the paper and whose variance is determined by the quality of the referees."
- Author Unknown1
Rethinking the immunotherapy numbers game
Rebecca A Bekker, Mohammad U Zahid, Jennifer M Binning, Bryan Q Spring, Patrick Hwu, Shari Pilon-Thomas, Heiko Enderling
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, …, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Data-Driven Simulation of Fisher-Kolmogorov Tumor Growth Models Using Dynamic Mode Decomposition
Alex Viguerie, Malú Grave, Gabriel F. Barros, Guillermo Lorenzo, Alessandro Reali, Alvaro Coutinho
Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes
Jason A. Somarelli, James DeGregori, Marco Gerlinger, Henry H. Heng, Andriy Marusyk, Danny R. Welch, Frank H. Laukien
Delaying Emergence of Resistance to KRAS Inhibitors with Adaptive Therapy: “Treatment-to-Contain” Instead of “Treatment-to-Cure”
Amir Imran Faisal Hamdi, Johnson Stanslas
Scales of Cancer Evolution: Selfish Genome or Cooperating Cells?
A Quantitative Characterization of the Spatial Distribution of Brain Metastases from Breast Cancer and Respective Molecular Subtypes
Saeedeh Mahmoodifar, Dhiraj J. Pangal, Tyler Cardinal, David Craig, Thomas Simon, Ben Yi Tew, Wensha Yang, Eric Chang, Min Yu, Josh Neman, Jeremy Mason, Arthur Toga, Bodour Salhia, Gabriel Zada, Paul K. Newton
High accuracy indicators of androgen suppression therapy failure for prostate cancer – a modeling study
William Meade, Allison Weber, Tin Phan, Emily Hampston, Laura Figueroa Resa, John Nagy, Yang Kuang
MathOnco Research Group Highlights
Saskia Haupt: We have launched a new feature for the MathOnco website: MathOnco Research Group Highlights. In this section of the website, we provide a world-wide overview of MathOnco research groups (https://mathematical-oncology.org/groups), that can be searched by keywords and geographic location.
Please consider reading and contributing this new Wikipedia page!
The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group.
Caption: “Have you ever wanted to visualize a histogram or density from counts of (x,y) pairs? Say if you wanted take a slice through a 2-dimensional density function along an arbitrary (non-linear) path? Look no further! Originally, the term ‘histo’ means mast, as in a sailboat mast that holds the luff of a sail. Here we call these a curvogram, which is a histogram on a curve that is given by a user defined function. To create these, orientated the bins so that they are perpendicular to the curve and performed a coordinate transform to ensure the edges are perpendicular to the curve at every point. To try this out yourself and help us develop this idea, you can find a MATLAB and Python version of our code here.“
Created by: Maximilian Strobl, Jeffrey West, Ryan Schenck, Sandy Anderson
Current subscriber count: >1.2k