This week in MathOnco 241

Cellular automata, cancer resistance, tumor heterogeneity, adaptive therapy, AI-assistance, and more.

“This week in Mathematical Oncology” — Feb. 2, 2023

> mathematical-oncology.org

From the editor:

Today we feature articles on cellular automata, cancer resistance, tumor heterogeneity, adaptive therapy, AI-assistance, and more.

Also, scroll down to the Jobs section to see more information about Moffitt’s first-ever postdoctoral recruitment event: “Moffitt Innovators of Tomorrow Symposium.”

Enjoy,

Jeffrey West
jeffrey.west@moffitt.org

---

“The dimmed outlines of phenomenal things all merge into one another unless we put on the focusing-glass of theory, and screw it up sometimes to one pitch of definition and sometimes to another, so as to see down into different depths through the great millstone of the world.”
- James Clerk Maxwell, "Are There Real Analogies in Nature?" (1856).

¹

---

1. Cellular-automaton model for tumor growth dynamics: Virtualization of different scenarios
   Carlos A. Valentim, José A. Rabi, Sergio A. David

2. Clustering by antigen-presenting genes reveals immune landscapes and predicts response to checkpoint immunotherapy
   Xutong Gong, Rachel Karchin

3. The Mystery of Cancer Resistance: A Revelation Within Nature
   Devangkumar D. Trivedi, Sarat Kumar Dalai, Sonal Rajiv Bakshi

4. Modeling tumour heterogeneity of PD-L1 expression in tumour progression and adaptive therapy
   Shizhao Ma, Jinzhi Lei, Xiulan Lai

5. An in silico model to study the impact of carbonic anhydrase IX expression on tumour growth and anti-PD-1 therapy
   Julia Grajek, Jakob Nikolas Kather, Jan Poleszczuk

6. A Systems Biology Approach for Addressing Cisplatin Resistance in Non-Small Cell Lung Cancer
   Sravani Ramisetty, Prakash Kulkarni, Supriyo Bhattacharya, Arin Nam, …, Swapnil Rajurkar, Erminia Massarelli, Ravi Salgia, Atish Mohanty

7. Implementing multiphysics models in FEniCS: Viscoelastic flows, poroelasticity, and tumor growth
   Birkan Tunç, Gregory J. Rodin, Thomas E. Yankeelov

1. Reading Between the Lines: Modeling User Behavior and Costs in AI-Assisted Programming
   Hussein Mozannar, Gagan Bansal, Adam Fourney, Eric Horvitz

2. The Lost Art of Mathematical Modelling
   Linnéa Gyllingberg, Abeba Birhane, David J.T. Sumpter

The newsletter now has a dedicated homepage where we post the cover artwork for each issue. We encourage submissions that coincide with the release of a recent paper from your group. This week’s artwork:

Artist: Ryan Schenck, with OpenAI

Caption: "This past week was the Computational Modelling of Cancer Biology and Treatments workshop hosted by Banff International Research Station in Banff, Alberta. The workshop was organized by Dr. Morgan Craig and Dr. Adrianne Jenner. In an effort to highlight the incredibly wide adoption of openAI and simultaneously draw attention to some of the communities ongoing conferences/workshops this week’s cover letter is an AI generated image given a prompt and then iteratively erasing and asking for revisions of different parts of the image. The initial request was to create ‘a painting of Lake Louise in Banff during the winter with a frozen lake.’ I then erased the sky and asked the AI to ‘add abstract mathematical equations in a blue sky.’ Once happy with the generated image, I erased the frozen lake and asked it to create ‘a team of scientists and doctors contemplating treatment for a cancer patient.’ The resulting image has no post-production and is the raw image from openAI."

Visit the mathematical oncology page to view jobs, meetings, and special issues. We will post new additions here, but the full list can found at mathematical-oncology.org.

1. Jobs

• Moffitt's Innovative Scholars of Tomorrow Postdoctoral Researcher Symposium

2. Conferences / Meetings

3. Special issues

---

Current subscriber count: >1.5k

1. H / T Mohammad Zahid (@MohammadUZahid)